Phenolic compounds as natural microbial toxin detoxifying agents

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dc.authoridGultekin Subasi, Busra/0000-0002-5304-3157
dc.authoridSaricaoglu, Beyza/0000-0002-8422-0478
dc.authoridKarbancioglu Guler, Funda/0000-0001-6576-0084
dc.contributor.authorSaricaoglu, Beyza
dc.contributor.authorSubasi, Buesra Gueltekin
dc.contributor.authorKarbancioglu-Guler, Funda
dc.contributor.authorLorenzo, Jose Manuel
dc.contributor.authorCapanoglu, Esra
dc.date.accessioned2024-10-26T18:09:29Z
dc.date.available2024-10-26T18:09:29Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractDespite the abundance of promising studies, developments, and improvements about the elimination of micro-bial toxins from food matrices, they are still considered as one of the major food safety problems due to the lack of their complete avoidance even today. Every year, many crops and foodstuffs have to be discarded due to unconstrained contamination and/or production of microbial toxins. Furthermore, the difficulty for the detection of toxin presence and determination of its level in foods may lead to acute or chronic health problems in many individuals. On the other hand, phenolic compounds might be considered as microbial toxin detoxification agents because of their inhibition effect on the toxin synthesis of microorganisms or exhibiting protective effects against varying damaging mechanisms caused by toxins. In this study, the effect of phenolic compounds on the synthesis of bacterial toxins and mycotoxins is comprehensively reviewed. The potential curing effect of phenolic compounds against toxin-induced damages has also been discussed. Consequently, phenolic compounds are indicated as promising, and considerable natural preservatives against toxin damages and their detoxification potentials are pronounced.
dc.description.sponsorship[IN607A201]
dc.description.sponsorshipJ.M. Lorenzo thanks to GAIN (Axencia Galega de Innovaci ' on) for supporting this review (grant number IN607A201) .
dc.identifier.doi10.1016/j.toxicon.2022.106989
dc.identifier.issn0041-0101
dc.identifier.issn1879-3150
dc.identifier.pmid36509264
dc.identifier.scopus2-s2.0-85144787063
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1016/j.toxicon.2022.106989
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30140
dc.identifier.volume222
dc.identifier.wosWOS:000992309300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofToxicon
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBacterial toxins
dc.subjectCholera toxin
dc.subjectMycotoxins
dc.subjectAflatoxin
dc.subjectPhenolic acid
dc.titlePhenolic compounds as natural microbial toxin detoxifying agents
dc.typeArticle

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