Digit Length Ratio as an Indicator of Fetal Androgen Levels: Relationship to Prostate Volume-Related Men Lower Urinary Tract Symptoms

Basit Öğe Kaydı
dc.authoridOzturk, Abuzer/0000-0002-6090-6133
dc.authoridERGIN, Ismail Emre/0000-0002-3115-0533
dc.contributor.authorErgin, Ismail Emre
dc.contributor.authorOzturk, Abuzer
dc.contributor.authorAsdemir, Aydemir
dc.date.accessioned2025-05-04T16:46:07Z
dc.date.available2025-05-04T16:46:07Z
dc.date.issued2025
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: This study aimed to investigate the relationship between the 2nd and 4th digit ratios, which are associated with fetal androgen exposure, and prostate volume and testosterone levels, both of which are linked to lower urinary tract symptoms (LUTS). Methods: Male patients presenting to our urology clinic with increased prostate volume and LUTS were categorized into two groups: those with BPH and those without (non-BPH). For both groups, the right-hand 2D:4D finger ratio, testosterone levels, prostate volume, uroflow parameters, and IPSS scores were recorded. Results: The 2D:4D ratio, prostate volumes, Qmax, and IPSS scores differed significantly between the BPH and non-BPH groups (p = 0.023, 0.002, 0.000, 0.001). No significant difference was observed in total testosterone levels between the groups (p = 0.381). The 2D:4D ratio was negatively correlated with prostate volume and IPSS (r = -0.389, -0.308) and positively correlated with Qmax (r = 0.301). Conclusions: Our study demonstrates that the 2D:4D ratio is a straightforward and effective tool for assessing BPH patients, as it correlates with the severity of LUTS symptoms. This non-invasive measure offers potential value in evaluating LUTS, and with age standardization, it could be applied more broadly across age groups. Further large-scale studies are needed to refine its standardization and expand upon current findings.
dc.identifier.doi10.1111/luts.70009
dc.identifier.issn1757-5664
dc.identifier.issn1757-5672
dc.identifier.issue2
dc.identifier.pmid39971879
dc.identifier.scopus2-s2.0-85218941442
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1111/luts.70009
dc.identifier.urihttps://hdl.handle.net/20.500.12418/35361
dc.identifier.volume17
dc.identifier.wosWOS:001426131900001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofLuts-Lower Urinary Tract Symptoms
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250504
dc.subject2D:4D ratio
dc.subjectLUTS
dc.subjectprostate volume
dc.titleDigit Length Ratio as an Indicator of Fetal Androgen Levels: Relationship to Prostate Volume-Related Men Lower Urinary Tract Symptoms
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksyonu
Scopus İndeksli Yayınlar Koleksiyonu