Mikania micrantha Kunth: An Ethnopharmacological Treasure Trove of Therapeutic Potential

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dc.authoridSharifi-Rad, Javad/0000-0002-7301-8151
dc.authoridBhuia, Md. Shimul/0000-0002-6179-9720
dc.authoridShill, Manik Chandra/0000-0002-0946-3816
dc.contributor.authorAli Khan, Muahmmad
dc.contributor.authorEl-Kersh, Dina M.
dc.contributor.authorIslam, Md. Shafiqul
dc.contributor.authorKhan, Shams Ara
dc.contributor.authorKamli, Hossam
dc.contributor.authorSarkar, Chandan
dc.contributor.authorBhuia, Md. Shimul
dc.date.accessioned2024-10-26T18:11:34Z
dc.date.available2024-10-26T18:11:34Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractMikania micrantha is utilized as a therapeutic for the treatment of various human ailments including insect bites, rashes and itches of skin, chicken pox, healing of sores and wounds, colds and fever, nausea, jaundice, rheumatism, and respiratory ailments. This study aimed at summarizing the traditional uses, phytochemical profile, and biological activities of M. micrantha based on obtainable information screened from different databases. An up-to-date search was performed on M. micrantha in PubMed, Science Direct, clinicaltrials.gov, and Google Scholar databases with specific keywords. No language restrictions were imposed. Published articles, theses, seminar/conference papers, abstracts, and books on ethnobotany, phytochemistry and pharmacological evidence were considered. Based on the inclusion criteria, this study includes 53 published records from the above-mentioned databases. The results suggest that fresh leaves and whole plant are frequently used in folk medicine. The plant contains more than 150 different phytochemicals under the following groups: essential oils, phenolics and flavonoids, terpenes, terpene lactones, glycosides, and sulfated flavonoids. It contains carbohydrates and micronutrients including vitamins and major and trace minerals. M. micrantha possesses antioxidant, anti-inflammatory, anti-microbial, anti-dermatophytic, anti-protozoal, anthelmintic, cytotoxic, anxiolytic, anti-diabetic, lipid-lowering and antidiabetic, spasmolytic, memory-enhancing, wound-healing, anti-aging, and thrombolytic activities. No clinical studies have been reported to date. M. micrantha might be one of the potential sources of phytotherapeutic compounds against diverse ailments in humans. Studies are required to confirm its safety profile in experimental animals prior to initiating clinical trials. Moreover, adequate investigation is also crucial to clarify exact mechanism of action for each biological effect.
dc.description.sponsorshipThe authors extend their appreciation to the Deanship of Scientific Research at King Khalid University for funding this work through large group Research Project under grant number RGP2/362/44. [RGP2/362/44]; Deanship of Scientific Research at King Khalid University
dc.description.sponsorshipThe authors extend their appreciation to the Deanship of Scientific Research at King Khalid University for funding this work through large group Research Project under grant number RGP2/362/44.
dc.identifier.doi10.1002/cbdv.202300392
dc.identifier.issn1612-1872
dc.identifier.issn1612-1880
dc.identifier.issue11
dc.identifier.pmid37715705
dc.identifier.scopus2-s2.0-85173868537
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1002/cbdv.202300392
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30740
dc.identifier.volume20
dc.identifier.wosWOS:001083380400001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley-V C H Verlag Gmbh
dc.relation.ispartofChemistry & Biodiversity
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMikania micrantha
dc.subjectclinical studies
dc.subjectfolk medicine
dc.subjectbiological activities
dc.subjecthuman ailments
dc.subjectphytotherapeutic compounds
dc.titleMikania micrantha Kunth: An Ethnopharmacological Treasure Trove of Therapeutic Potential
dc.typeReview Article

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