Chemical Composition, Antioxidant, Antimicrobial and Antispasmodic Activities of the Essential Oil of Juniperus excelsa subsp excelsa

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dc.authoridVURAL, Nilufer -- 0000-0003-3047-3004en_US
dc.contributor.authorAtas, Ahmet Duran
dc.contributor.authorGoze, Ismihan
dc.contributor.authorAlim, Ahmet
dc.contributor.authorCetinus, Senay Akkus
dc.contributor.authorDurmus, Nedim
dc.contributor.authorVural, Nilufer
dc.contributor.authorCakmak, Osman
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:04:12Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:04:12Z
dc.date.issued2012
dc.department[Atas, Ahmet Duran] Cumhuriyet Univ, Fac Vet Med, Dept Parasitol, Sivas, Turkey -- [Goze, Ismihan] Cumhuriyet Univ, Vocat Sch Hlth Serv, Sivas, Turkey -- [Alim, Ahmet] Cumhuriyet Univ, Fac Vet Med, Dept Microbiol, Sivas, Turkey -- [Cetinus, Senay Akkus] Cumhuriyet Univ, Fac Sci & Literature, Dept Chem, Sivas, Turkey -- [Durmus, Nedim] Cumhuriyet Univ, Sch Med, Dept Pharmacol, Sivas, Turkey -- [Vural, Nilufer] Ankara Univ, Inst Biotechnol, TR-06100 Ankara, Turkey -- [Cakmak, Osman] Gaziosmanpasa Univ, Fac Art & Sci, Dept Chem, Tokat, Turkeyen_US
dc.description.abstractIn this study, chemical composition, antioxidant, antimicrobial and antiospasmodic activities of the essential oil of the berries Juniperus excelsa Bieb. subsp. excelsa were evaluated in vitro. GC and GS-MS analysis of the oil resulted in the identification of 25 compounds, representing 97.2 % of the oil; alpha-pinene (46.1 %) was the main component. Essential oil showed remarkable antimicrobial activity against the test microorganisms. The sample was also subjected to a screening for its possible antioxidant activity by using 2,2-diphenyl-1- picrylhydrazyl (DPPH) and beta-carotene-linoleic acid assays. It was exhibited moderate antioxidant activity in beta-carotene-linoleic acid test system. In rat ileum, J. excelsa essential oil effect was directly investigated on spontaneous contractions. It has been found that amplitude and frequency did not change significantly at all dose concentrations. Amplitude has been inhibited % 25 and frequency has been inhibited % 20 at 1 mg/mL.en_US
dc.identifier.doi10.1080/0972060X.2012.10644075en_US
dc.identifier.endpage483en_US
dc.identifier.issn0972-060X
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84869399648en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage476en_US
dc.identifier.urihttps://dx.doi.org/10.1080/0972060X.2012.10644075
dc.identifier.urihttps://hdl.handle.net/20.500.12418/9263
dc.identifier.volume15en_US
dc.identifier.wosWOS:000321518000019en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofJOURNAL OF ESSENTIAL OIL BEARING PLANTSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectJuniperus excelsaen_US
dc.subjectessential oilen_US
dc.subjectantioxidanten_US
dc.subjectantimicrobialen_US
dc.subjectantispasmodicen_US
dc.titleChemical Composition, Antioxidant, Antimicrobial and Antispasmodic Activities of the Essential Oil of Juniperus excelsa subsp excelsaen_US
dc.typeArticleen_US

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