Acute retinal necrosis: clinical features, management and outcomes

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dc.authoridozdemir yalcinsoy, kubra/0000-0002-3352-9547
dc.contributor.authorYalcinsoy, Kubra Ozdemir
dc.contributor.authorOzdal, Pinar Cakar
dc.contributor.authorTekin, Merve Inanc
dc.contributor.authorKaratepe, Mustafa Salih
dc.contributor.authorErol, Yasemin Ozdamar
dc.date.accessioned2024-10-26T18:09:02Z
dc.date.available2024-10-26T18:09:02Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractPurpose To evaluate the clinical features, treatment, and visual outcome of patients with acute retinal necrosis (ARN). Methods The data of patients were retrospectively reviewed. Factors associated with visual loss and factors affecting the risk for retinal detachment (RD) development were evaluated. Results Twenty-four eyes of 24 patients (7 female/17 male, mean age 43.7 years, mean follow-up period 31.0 months) were included. In ocular fluid samples of 15 (83%) out of 18 eyes, polymerase chain reaction (PCR) tests were positive for herpes simplex virus (seven eyes; 39%), varicella zoster virus (six eyes; 33%), cytomegalovirus (one eye; 6%), and adenovirus (one eye; 6%). Central retinal occlusive vasculitis was observed in three (13%) eyes. Systemic antiviral therapy was given to all patients, and additional intravitreal ganciclovir was administered in seven eyes (29%). The most common complication was RD (46%). There was no statistically significant difference in the frequency of RD between herpes simplex virus- and varicella zoster virus-positive patients (p = .617). The rate of RD was similar in eyes undergoing prophylactic laser photocoagulation (LPC), eyes undergoing vitrectomy + LPC, and eyes not undergoing LPC (p = .237). The number of eyes with final visual acuity below 20/200 was significantly higher in eyes with RD than without RD (p = .047). Conclusion Prophylactic LPC and vitrectomy did not show clear benefits in terms of preventing RD development. RD was the most common complication and a major factor for a poor visual prognosis.
dc.identifier.doi10.1007/s10792-022-02598-7
dc.identifier.endpage1994
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue6
dc.identifier.pmid36436167
dc.identifier.scopus2-s2.0-85142679967
dc.identifier.scopusqualityQ2
dc.identifier.startpage1987
dc.identifier.urihttps://doi.org/10.1007/s10792-022-02598-7
dc.identifier.urihttps://hdl.handle.net/20.500.12418/29922
dc.identifier.volume43
dc.identifier.wosWOS:000889051600001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofInternational Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcute retinal necrosis
dc.subjectOcclusive vasculitis
dc.subjectAntiviral therapy
dc.subjectRetinal detachment
dc.subjectLaser photocoagulation
dc.subjectVitrectomy
dc.titleAcute retinal necrosis: clinical features, management and outcomes
dc.typeArticle

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