Distribution of Urinary System Infection Agents in Children and Evaluation of Their Susceptibility to Antibiotics

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dc.contributor.authorKafa, Ayse Huemeyra Taskin
dc.contributor.authorCubuk, Fatih
dc.contributor.authorAkbulut, Resul Ekrem
dc.contributor.authorHasbek, Muersit
dc.contributor.authorTastanoglu, Hueseyin
dc.date.accessioned2024-10-26T18:05:19Z
dc.date.available2024-10-26T18:05:19Z
dc.date.issued2024
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractIntroduction: Urinary tract infection (UTI) is among the common bacterial infections in pediatric patients. These infections are more common in girls over one year old. This study aimed to investigate the bacterial distribution and drug resistance status in urine cultures of pediatric patients in our center. Materials and Methods: Urine culture results of patients who were presented to the outpatient clinics or were admitted to the Sivas Cumhuriyet University hospital between January 2017 and December 2022 were included in the study. The hospital automation system, patient files, and laboratory information management system were examined retrospectively. Statistical analysis was performed using the SPSS 22.0 software. A P -value of <0.05 was deemed significant. Results: Significant growth was observed in the urine cultures of a total of 1287 pediatric patients, 889 (69.1%) girls and 398 boys (30.9%). The patients included in the study were between the ages of 0-17, and children aged 1-6 (37.6%) were diagnosed with UTI more frequently than other ages. The most common UTI agent in the pediatric age group was Escherichia coli (56.6%). The first agent isolated in girls and boys is E.coli . Additionally, the prevalence of K. pneumoniae, P. mirabilis and K. oxytoca bacteria was higher in boys (p < 0.05). E. coli isolates showed minimal resistance to such as amikacin (0.6%), fosfomycin (1.0%), nitrofurantoin (1.4%), ertapenem (2.4%), imipenem (0.7%) and meropenem (0.9%). Conclusion: In this study, low resistance levels were detected for amikacin, fosfomycin, nitrofurantoin and carbapenem group antibiotics, which are important alternatives in the empirical treatment of UTI. On the other hand, due to the high resistance levels detected, it is thought that more caution should be exercised in the empirical use of amoxicillin-clavulanate, trimethoprimsulfamethoxazole and cefixime. If these antibiotics are to be preferred, waiting for the antibiogram results is an appropriate approach.
dc.identifier.doi10.4274/jcp.2024.62444
dc.identifier.endpage30
dc.identifier.issn1304-9054
dc.identifier.issn1308-6308
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85193283734
dc.identifier.scopusqualityQ4
dc.identifier.startpage24
dc.identifier.urihttps://doi.org/10.4274/jcp.2024.62444
dc.identifier.urihttps://hdl.handle.net/20.500.12418/28939
dc.identifier.volume22
dc.identifier.wosWOS:001218307400007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherGalenos Publ House
dc.relation.ispartofGuncel Pediatri-Journal of Current Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectUrinary tract infection
dc.subjectdrug resistance
dc.subjectpediatric
dc.titleDistribution of Urinary System Infection Agents in Children and Evaluation of Their Susceptibility to Antibiotics
dc.typeArticle

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