Assessment of the New 2012 EULAR/ACR Clinical Classification Criteria for Polymyalgia Rheumatica: A Prospective Multicenter Study

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dc.authoridOzen, Gulsen -- 0000-0002-5423-393Xen_US
dc.contributor.authorOzen, Gulsen
dc.contributor.authorInanc, Nevsun
dc.contributor.authorUnal, Ali Ugur
dc.contributor.authorBas, Seda
dc.contributor.authorKimyon, Gezmis
dc.contributor.authorKisacik, Bunyamin
dc.contributor.authorOnat, Ahmet Mesut
dc.contributor.authorMurat, Sadiye
dc.contributor.authorKeskin, Havva
dc.contributor.authorCan, Meryem
dc.contributor.authorMengi, Alperen
dc.contributor.authorCakir, Necati
dc.contributor.authorBalkarli, Ayse
dc.contributor.authorCobankara, Veli
dc.contributor.authorYilmaz, Neslihan
dc.contributor.authorYazici, Ayten
dc.contributor.authorDogru, Atalay
dc.contributor.authorSahin, Mehmet
dc.contributor.authorSahin, Ali
dc.contributor.authorGok, Kevser
dc.contributor.authorSenel, Soner
dc.contributor.authorPamuk, Omer Nuri
dc.contributor.authorYilmaz, Sema
dc.contributor.authorBayindir, Ozun
dc.contributor.authorAksu, Kenan
dc.contributor.authorCagatay, Yonca
dc.contributor.authorAkyol, Lutfi
dc.contributor.authorSayarlioglu, Mehmet
dc.contributor.authorYildirim-Cetin, Gozde
dc.contributor.authorYasar-Bilge, Sule
dc.contributor.authorYagci, Ilker
dc.contributor.authorAydin, Sibel Zehra
dc.contributor.authorAlibaz-Oner, Fatma
dc.contributor.authorAtagunduz, Pamir
dc.contributor.authorDireskeneli, Haner
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:45:28Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:45:28Z
dc.date.issued2016
dc.department[Ozen, Gulsen -- Inanc, Nevsun -- Unal, Ali Ugur -- Bas, Seda -- Alibaz-Oner, Fatma -- Atagunduz, Pamir -- Direskeneli, Haner] Marmara Univ, Fac Med, Dept Rheumatol, Muhsin Yazicioglu Str 10, TR-34890 Istanbul, Turkey -- [Yagci, Ilker] Marmara Univ, Fac Med, Dept Phys Therapy & Rehabil, Istanbul, Turkey -- [Murat, Sadiye -- Keskin, Havva] Goztepe Medeniyet Univ, Fac Med, Dept Phys Med & Rehabil, Istanbul, Turkey -- [Can, Meryem -- Mengi, Alperen -- Cakir, Necati] Fatih Sultan Mehmet Educ & Res Hosp, Dept Rheumatol, Istanbul, Turkey -- [Yilmaz, Neslihan -- Cagatay, Yonca] Bilim Univ, Fac Med, Dept Rheumatol, Istanbul, Turkey -- [Kimyon, Gezmis -- Kisacik, Bunyamin -- Onat, Ahmet Mesut] Gaziantep Univ, Fac Med, Dept Rheumatol, Gaziantep, Turkey -- [Balkarli, Ayse -- Cobankara, Veli] Pamukkale Univ, Fac Med, Dept Rheumatol, Denizli, Turkey -- [Yazici, Ayten] Sakarya Educ & Res Hosp, Dept Rheumatol, Sakarya, Turkey -- [Dogru, Atalay -- Sahin, Mehmet] Suleyman Demirel Univ, Dept Rheumatol, Isparta, Turkey -- [Sahin, Ali] Cumhuriyet Univ, Fac Med, Dept Rheumatol, Sivas, Turkey -- [Gok, Kevser -- Senel, Soner] Erciyes Univ, Fac Med, Dept Rheumatol, Kayseri, Turkey -- [Pamuk, Omer Nuri] Trakya Univ, Fac Med, Dept Rheumatol, Edirne, Turkey -- [Yilmaz, Sema] Selcuk Univ, Selcuklu Fac Med, Dept Rheumatol, Konya, Turkey -- [Bayindir, Ozun -- Aksu, Kenan] Ege Univ, Fac Med, Dept Rheumatol, Izmir, Turkey -- [Akyol, Lutfi -- Sayarlioglu, Mehmet] Ondokuz Mayis Univ, Fac Med, Dept Rheumatol, Samsun, Turkey -- [Yildirim-Cetin, Gozde] Sutcu Imam Univ, Fac Med, Dept Rheumatol, Kahramanmaras, Turkey -- [Yasar-Bilge, Sule] Yunus Emre Govt Hosp, Dept Rheumatol, Eskisehir, Turkey -- [Aydin, Sibel Zehra] Univ Ottawa, Sch Med, Dept Rheumatol, Ottawa, ON, Canadaen_US
dc.description.abstractObjective. To assess the performance of the new 2012 provisional European League Against Rheumatism (EULAR)/ American College of Rheumatology (ACR) polymyalgia rheumatica (PMR) clinical classification criteria in discriminating PMR from other mimicking conditions compared with the previous 5 diagnostic criteria in a multicenter prospective study. Methods. Patients older than 50 years, presenting with new-onset bilateral shoulder pain with elevated acute-phase reactants (APR), were assessed for the fulfillment of the new and old classification/diagnostic criteria sets for PMR. At the end of the 1-year followup, 133 patients were diagnosed with PMR (expert opinion) and 142 with non-PMR conditions [69 rheumatoid arthritis (RA)]. Discriminating capacity, sensitivity, and specificity of the criteria sets were estimated. Results. Discriminating capacity of the new clinical criteria for PMR from non-PMR conditions and RA as estimated by area under the curve (AUC) were good with AUC of 0.736 and 0.781, respectively. The new criteria had a sensitivity of 89.5% and a specificity of 57.7% when tested against all non-PMR cases. When tested against all RA, seropositive RA, seronegative RA, and non-RA control patients, specificity changed to 66.7%, 100%, 20.7%, and 49.3%, respectively. Except for the Bird criteria, the 4 previous criteria had lower sensitivity and higher specificity (ranging from 83%-93%) compared with the new clinical criteria in discriminating PMR from all other controls. Conclusion. The new 2012 EULAR/ ACR clinical classification criteria for PMR is highly sensitive; however, its ability to discriminate PMR from other inflammatory/noninflammatory shoulder conditions, especially from seronegative RA, is not adequate. Imaging and other modifications such as cutoff values for APR might increase the specificity of the criteria.en_US
dc.identifier.doi10.3899/jrheum.151103en_US
dc.identifier.endpage900en_US
dc.identifier.issn0315-162X
dc.identifier.issn1499-2752
dc.identifier.issue5en_US
dc.identifier.pmid26834222en_US
dc.identifier.scopus2-s2.0-84969262510en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage893en_US
dc.identifier.urihttps://dx.doi.org/10.3899/jrheum.151103
dc.identifier.urihttps://hdl.handle.net/20.500.12418/7337
dc.identifier.volume43en_US
dc.identifier.wosWOS:000380854200011en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJ RHEUMATOL PUBL COen_US
dc.relation.ispartofJOURNAL OF RHEUMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPOLYMYALGIA RHEUMATICAen_US
dc.subjectCLASSIFICATION CRITERIAen_US
dc.subjectRHEUMATOID ARTHRITISen_US
dc.titleAssessment of the New 2012 EULAR/ACR Clinical Classification Criteria for Polymyalgia Rheumatica: A Prospective Multicenter Studyen_US
dc.typeArticleen_US

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