Myristicin: From its biological effects in traditional medicine in plants to preclinical studies and use as ecological remedy in plant protection

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dc.authoridBUTNARIU, Monica/0000-0002-2032-5000
dc.authoridMartorell, Miquel/0000-0003-3183-7623
dc.authoridSharifi-Rad, Javad/0000-0002-7301-8151
dc.authoridIqbal, Mehwish/0000-0003-0186-3679
dc.authoridRamirez-Alarcon, Karina/0000-0003-0560-7154
dc.contributor.authorRamirez-Alarcon, Karina
dc.contributor.authorMartorell, Miquel
dc.contributor.authorGurer, Eda Sonmez
dc.contributor.authorLaher, Ismail
dc.contributor.authorLam, Hei-Long
dc.contributor.authorMohieldin, Ebtihal Abdalla M.
dc.contributor.authorMuddathir, Ali Mahoumd
dc.date.accessioned2024-10-26T18:11:38Z
dc.date.available2024-10-26T18:11:38Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractMyristicin is an allylbenzene and a major key constituent of many plant species, such as Myristica fragrans Houtt. (nutmeg), Foeniculum vulgare Mill. (fennel), and Petroselinum crispum (Mill.) Fuss (parsley). Their plant parts have been used in traditional medicine and as a flavoring seasoning for cooking but, and as biopesticides with natural compounds. Myristicin has been related with several biological effects, such as anticarcinogenic, anti-inflammatory, antimicrobial, antioxidant, antidiabetic, analgesic, and hepatoprotective. The traditional uses include the treatment of complications related to gastrointestinal tract, respiratory system, and gynecological disorders. However, several studies have been reported contraindications associated to high dose consumption of myristicin. This review summarizes the biological activities of myristicin and myristicin-rich plants, toxicological effects along with its bioavailability, and metabolism. In addition, their traditional uses and their role as ecological remedy in plants protection has been reviewed. Nutmeg is the myristicin-rich plant with more pharmacological effects reported but also with most contraindication and toxically reports. The aim of the present review is to highlight the traditional uses and pharmacological activities of myristicin-rich plants along with their contraindications and bioavailability.image
dc.description.sponsorshipNone [ACE210012]
dc.description.sponsorshipThis work was supported by ANID CENTROS BASALES ACE210012. Some of the components in Figures 1 and 2 are developed using vector graphics from .
dc.identifier.doi10.1002/efd2.90
dc.identifier.issn2666-3066
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85191731666
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://doi.org/10.1002/efd2.90
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30769
dc.identifier.volume4
dc.identifier.wosWOS:001136675100002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofEfood
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectgreen ecology
dc.subjectmyristicin
dc.subjectnutmeg
dc.subjectparsley
dc.subjectphytotherapy
dc.subjecttoxicity
dc.subjecttraditional medicine
dc.titleMyristicin: From its biological effects in traditional medicine in plants to preclinical studies and use as ecological remedy in plant protection
dc.typeReview Article

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