The effect of the gastrectomy on survival in patients with metastatic gastric cancer: a study of ASMO

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dc.authoridAksoy, Sercan -- 0000-0003-4984-1049; aksoy, asude -- 0000-0002-5609-9658en_US
dc.contributor.authorYazici, Ozan
dc.contributor.authorOzdemir, Nuriye
dc.contributor.authorDuran, Ayse Ocak
dc.contributor.authorMenekse, Serkan
dc.contributor.authorAli, Mehmet
dc.contributor.authorSendur, Nahit
dc.contributor.authorKaraca, Halit
dc.contributor.authorGoksel, Gamze
dc.contributor.authorArpaci, Erkan
dc.contributor.authorHacibekiroglu, Ilhan
dc.contributor.authorBilgetekin, Irem
dc.contributor.authorKacan, Turgut
dc.contributor.authorOzkan, Metin
dc.contributor.authorAksoy, Sercan
dc.contributor.authorAksoy, Asude
dc.contributor.authorCokmert, Suna
dc.contributor.authorUysal, Mukremin
dc.contributor.authorElkiran, Emin Tamer
dc.contributor.authorCicin, Irfan
dc.contributor.authorBuyukberber, Suleyman
dc.contributor.authorZengin, Nurullah
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:47:05Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:47:05Z
dc.date.issued2016
dc.department[Yazici, Ozan -- Aksoy, Sercan -- Zengin, Nurullah] Ankara Numune Training & Res Hosp, Dept Med Oncol, TR-06410 Ankara, Turkey -- [Ozdemir, Nuriye -- Sendur, Nahit] Yildirim Beyazit Univ, Fac Med, Dept Med Oncol, TR-06800 Ankara, Turkey -- [Duran, Ayse Ocak -- Karaca, Halit -- Ozkan, Metin] Erciyes Univ, Fac Med, Dept Med Oncol, TR-38030 Kayseri, Talas Melikgazi, Turkey -- [Menekse, Serkan -- Goksel, Gamze] Celal Bayar Univ, Fac Med, Dept Med Oncol, TR-45030 Uncubozkoy, Manisa, Turkey -- [Arpaci, Erkan] Sakarya Univ, Educ & Res Hosp, Dept Med Oncol, TR-54100 Sirinevler, Sakarya, Turkey -- [Hacibekiroglu, Ilhan] Trakya Univ, Fac Med, Dept Med Oncol, TR-22050 Karaagac, Edirne, Turkey -- [Bilgetekin, Irem -- Buyukberber, Suleyman] Gazi Univ, Fac Med, Dept Med Oncol, TR-06560 Emniyet, Ankara, Turkey -- [Kacan, Turgut] Cumhuriyet Univ, Fac Med, Dept Med Oncol, TR-58140 Sivas, Imaret, Turkey -- [Aksoy, Sercan -- Elkiran, Emin Tamer] Inonu Univ, Fac Med, Dept Med Oncol, TR-44000 Malatya, Centre, Turkey -- [Cokmert, Suna] Izmir Kent Hosp, Dept Med Oncol, Izmir, Turkey -- [Uysal, Mukremin] Afyon Kocatepe Univ, Fac Med, Afyon, Turkeyen_US
dc.description.abstractAim: To investigate the role of surgical resection of primary tumor on overall survival (OS) in advanced gastric cancer patients at the time of diagnosis. Patients & methods: The survival rates of metastatic gastric cancer patients whose gastric primary tumor was resected at time of diagnosis were compared with metastatic gastric cancer patients whose primary tumor was nonresected. Results: The median progression-free survival and OS in operated and nonoperated group were 10 versus 6, 14 versus 9 months, respectively (p < 0.001). In multivariate analysis, gastric resection of primary tumor, Eastern Cooperative Oncology Group performance status, second-line chemotherapy had a significant effect on OS (hazard ratio [HR]: 0.52 [95% CI: 0.38-0.71], HR: 0.57 [95% CI: 0.42-0.78], HR: 1.48 [1.09-2.01]; p <= 0.001, p = 0.001 and p = 0.012, respectively). Conclusion: Subpopulations of patients with metastatic gastric cancer might benefit from surgical removal of primary tumor.en_US
dc.identifier.doi10.2217/fon.15.304en_US
dc.identifier.endpage354en_US
dc.identifier.issn1479-6694
dc.identifier.issn1744-8301
dc.identifier.issue3en_US
dc.identifier.pmid26775722en_US
dc.identifier.scopus2-s2.0-84956466822en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage343en_US
dc.identifier.urihttps://dx.doi.org/10.2217/fon.15.304
dc.identifier.urihttps://hdl.handle.net/20.500.12418/7623
dc.identifier.volume12en_US
dc.identifier.wosWOS:000368937200011en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherFUTURE MEDICINE LTDen_US
dc.relation.ispartofFUTURE ONCOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectadvanced gastric canceren_US
dc.subjectgastrectomyen_US
dc.subjectresectionen_US
dc.subjectsurvivalen_US
dc.titleThe effect of the gastrectomy on survival in patients with metastatic gastric cancer: a study of ASMOen_US
dc.typeArticleen_US

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