Antioxidant properties of methanolic extract of 'Veronica multifida' and DFT and HF analyses of its the major flavonoid component

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dc.authoridUngordu, Ayhan/0000-0002-7543-8379
dc.contributor.authorKoc, Emre
dc.contributor.authorUngordu, Ayhan
dc.contributor.authorCandan, Ferda
dc.date.accessioned2024-10-26T18:03:50Z
dc.date.available2024-10-26T18:03:50Z
dc.date.issued2019
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractThe experimental part of this study, investigated the effects of a methanolic extract of Veronica multifida on total phenolic and flavonoid content, antioxidant capacities; and DPPH scavenging activity. The methanol extract of V. multifida showed an equivalent of phenolic content of 196.67 mg gallic acid per gram dry weight, flavonoid content of 206.17 mg quercetin per gram dry weight and total antioxidant capacities of 134.41 mM alpha-tocopherol acetate per gram dry weight. Additionally, the amount of extract supplying 50% inhibition of DPPH was assayed as 66.65 mg L-1. The V. multifida plant extract to be used in the study was reported to contain luteolin as its main flavonoid component. The luteolin content of 0.2-0.5 mu g g(-1) was reported to be within the normal concentration range. Additionally, the antioxidant properties of luteolin were theoretically examined and compared to butylated hydroxytoluene and curcumin, which are respectively synthetic and natural antioxidants. The density functional theory (DFT) and Hartree-Fock methods were used in all calculations. The most stable structures of molecules were determined by using the B3LYP functional with the 6-311G(d,p) basis set. The theoretical methods showed that the antioxidant properties of pure luteolin are similar to those of butylated hydroxytoluene. (C) 2019 Elsevier B.V. All rights reserved.
dc.identifier.doi10.1016/j.molstruc.2019.07.056
dc.identifier.endpage442
dc.identifier.issn0022-2860
dc.identifier.issn1872-8014
dc.identifier.scopus2-s2.0-85069628594
dc.identifier.scopusqualityQ2
dc.identifier.startpage436
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2019.07.056
dc.identifier.urihttps://hdl.handle.net/20.500.12418/28598
dc.identifier.volume1197
dc.identifier.wosWOS:000487932000046
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofJournal of Molecular Structure
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectVeronica multifida
dc.subjectAntioxidant
dc.subjectLuteolin
dc.subjectDFT
dc.titleAntioxidant properties of methanolic extract of 'Veronica multifida' and DFT and HF analyses of its the major flavonoid component
dc.typeArticle

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