Pruritus is not sensorial in psoriasis: the mutual interactions between dermatologic life quality and pruritus

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dc.contributor.authorHayta, Sibel Berksoy
dc.contributor.authorGuner, Rukiye
dc.contributor.authorAkyol, Melih
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:37:05Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:37:05Z
dc.date.issued2019
dc.department[Hayta, Sibel Berksoy -- Guner, Rukiye -- Akyol, Melih] Cumhuriyet Univ, Sch Med, Dept Dermatol, Sivas, Turkeyen_US
dc.description.abstractBACKGROUND: Pruritus may emerge as affective or sensorial in psoriasis patients. It is not known whether the mediating effect of pruritus or disease severity on the quality of life is more pronounced. This study was conducted to determine the mediating effects and interactions between disease severity, pruritus and life quality in psoriasis patients. METHODS: 105 patients with psoriasis vulgaris were included in the study. Psoriasis Area and Severity Index (PAST) values, Dermatology Life Quality Index (DLQI), and visual analog scales for pruritus of each patient were analyzed by determining the correlations and the mediating interactions between these parameters. RESULTS: There was a moderate correlation between pruritus and DLQI (P=0.0001, r=0,528), a weak correlation between pruritus and PASI (P=0.005, r=0.273) and a moderate correlation between PASI and DLQI. The mediation effects of DLQI to pruritus, PASI to pruritus, PASI to DLQI and pruritus to DLQI were 25%, 0.047%, 22% and 25%, respectively. Also, the mediation effect of PASI plus pruritus to DLQI was 38%. CONCLUSIONS: The most obvious factor for pruritus is the impairment of DLQI rather than PASI in psoriasis patients. The mediating effect of PASI to DLQI increases the pruritus significantly.en_US
dc.identifier.doi10.23736/S0393-3660.18.03805-6en_US
dc.identifier.endpage306en_US
dc.identifier.issn0393-3660
dc.identifier.issn1827-1812
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85064207418en_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage301en_US
dc.identifier.urihttps://dx.doi.org/10.23736/S0393-3660.18.03805-6
dc.identifier.urihttps://hdl.handle.net/20.500.12418/5915
dc.identifier.volume178en_US
dc.identifier.wosWOS:000465640200009en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherEDIZIONI MINERVA MEDICAen_US
dc.relation.ispartofGAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPsoriasisen_US
dc.subjectPruritusen_US
dc.subjectQuality of lifeen_US
dc.titlePruritus is not sensorial in psoriasis: the mutual interactions between dermatologic life quality and pruritusen_US
dc.typeArticleen_US

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