Supercharging metabolic health with Lycium barbarum L.: A review of the therapeutic potential of this functional food for managing metabolic syndrome

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dc.authoridZivkovic, Jelena/0000-0002-9684-2637
dc.authoridSharifi-Rad, Javad/0000-0002-7301-8151
dc.authoridKilic, Ceyda Sibel/0000-0003-2905-7628
dc.contributor.authorSharifi-Rad, Javad
dc.contributor.authorQuetglas-Llabres, Maria Magdalena
dc.contributor.authorSureda, Antoni
dc.contributor.authorMardones, Lorena
dc.contributor.authorVillagran, Marcelo
dc.contributor.authorGurer, Eda Sonmez
dc.contributor.authorZivkovic, Jelena
dc.date.accessioned2024-10-26T18:11:43Z
dc.date.available2024-10-26T18:11:43Z
dc.date.issued2024
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractMetabolic syndrome (MetS) is a common disorder involving a cluster of metabolic abnormalities, such as abdominal obesity, hypertension, dyslipidemia, insulin resistance, and atherogenic profile. MetS is characterized by an increase in oxidative stress and a chronic proinflammatory state, which are directly related to the development and progression of this pathology. It has been seen how a healthy lifestyle and good dietary practices are key to improving the different metabolic parameters and, therefore, play a fundamental role in reducing the risk of developing diabetes. The present review focuses on the research evidence related to the therapeutic properties of Lycium barbarum L. in MetS gathered in the last years. Several preclinical studies suggest that L. barbarum extracts are a good dietary supplement for the prevention of cardiovascular diseases in people with MetS. This compound has been used for years in traditional Chinese medicine for the treatment of atrophic gastritis, problems related to the lungs, kidneys, and liver, and as a supplement for eye health. In addition, different in vitro and in vivo studies have been carried out that support the properties attributed to metabolites derived from L. barbarum, such as polysaccharides that have been shown diverse biological activities. In conclusion, L. barbarum extracts have multiple benefits to increase general well-being and immune function. However, there are a limited number of studies related to effect of L. barbarum in MetS, but they demonstrated effectiveness in the treatment of obesity, diabetes mellitus type 2, and prevention of diabetes mellitus type 2 complication.
dc.description.sponsorshipInstituto de Salud Carlos [CIBEROBN CB12/03/30038]
dc.description.sponsorshipInstituto de Salud Carlos, Grant/Award Number: CIBEROBNCB12/03/30038
dc.identifier.doi10.1002/fft2.327
dc.identifier.endpage434
dc.identifier.issn2643-8429
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85181678111
dc.identifier.scopusqualityN/A
dc.identifier.startpage420
dc.identifier.urihttps://doi.org/10.1002/fft2.327
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30779
dc.identifier.volume5
dc.identifier.wosWOS:001139603200001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofFood Frontiers
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectgoji
dc.subjectimmune system
dc.subjectLycium barbarum
dc.subjectmetabolic syndrome
dc.subjectoxidative stress
dc.subjectpolysaccharides
dc.titleSupercharging metabolic health with Lycium barbarum L.: A review of the therapeutic potential of this functional food for managing metabolic syndrome
dc.typeReview Article

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