Does decision tree analysis predict oral ulcer activity-related factors in patients with Behçet's syndrome?

dc.authoridYay, Meral/0000-0003-1857-8719
dc.authoridKaradag, Omer/0000-0002-3443-3117
dc.authoridOzdamar, Elif Ozge/0000-0001-5652-1858
dc.authoridCandereli, Zehra Ozge/0000-0003-4616-2761
dc.contributor.authorCandereli, Z. O.
dc.contributor.authorArslan, T.
dc.contributor.authorOzdamar, O.
dc.contributor.authorYay, M.
dc.contributor.authorKaracayli, U.
dc.contributor.authorSisman-Kitapci, N.
dc.contributor.authorAdesanya, A.
dc.date.accessioned2024-10-26T18:11:43Z
dc.date.available2024-10-26T18:11:43Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective The study aimed to identify the interactions among treatment protocols and oral ulcer activity related factors in patients with Behcet's syndrome (BS) using the Classification and Regression Tree (CART) algorithm. Methods In this cross-sectional study, 979 patients with BS were included from16 centres in Turkey, Jordan, Brazil and the United Kingdom. In the CART algorithm, activities of oral ulcer (active vs. inactive), genital ulcer (active vs. inactive), cutaneous involvement (active vs. inactive), musculoskeletal involvement (active vs. inactive), gender (male vs. female), disease severity (mucocutaneous and musculoskeletal involvement vs. major organ involvement), smoking habits (current smoker vs. non-smoker), tooth brushing habits (irregular vs. regular), were input variables. The treatment protocols regarding immunosuppressive (IS) or non-IS medications were the target variable used to split from parent nodes to purer child nodes in the study. Results In mucocutaneous and musculoskeletal involvement (n=538), the ratio of IS use was higher in patients with irregular toothbrushing (ITB) habits (27.1%) than in patients with regular toothbrushing (RTB) habits (14.2%) in oral ulcer activity. In major organ involvement (n=441), male patients with ITB habits were more likely treated with IS medications compared to those with RTB habits (91.6% vs. 77.6%, respectively). Conclusion Male BS patients on IS who have major organ involvement and oral ulcer activity with mucocutaneous and musculoskeletal involvement have irregular toothbrushing habits. Improved oral hygiene practices should be considered to be an integral part for implementing patient empowerment strategies for BS.
dc.identifier.endpage2086
dc.identifier.issn0392-856X
dc.identifier.issn1593-098X
dc.identifier.issue10
dc.identifier.pmid37902270
dc.identifier.scopus2-s2.0-85175405511
dc.identifier.scopusqualityQ2
dc.identifier.startpage2078
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30778
dc.identifier.volume41
dc.identifier.wosWOS:001098661500018
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherClinical & Exper Rheumatology
dc.relation.ispartofClinical and Experimental Rheumatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBehcet's syndrome
dc.subjectoral ulcer
dc.subjectdecision tree analysis
dc.titleDoes decision tree analysis predict oral ulcer activity-related factors in patients with Behçet's syndrome?
dc.typeArticle

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