The Relationship between the SUVmax Value Obtained in Ga-68 PSMA PET/CT and Lactate Dehydrogenase and Alkaline Phosphatase in Prostate Cancer

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dc.contributor.authorErturk, Seyit Ahmet
dc.contributor.authorSalk, Ismail
dc.contributor.authorYuecel, Birsen
dc.contributor.authorBabacan, Ozge Ulas
dc.contributor.authorHasbek, Zekiye
dc.date.accessioned2024-10-26T18:05:27Z
dc.date.available2024-10-26T18:05:27Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjectives: ALP and LDH are serum markers of prognostic importance in prostate cancer patients. PET/CT imaging with Ga-68 PSMA has played an important role in prostate cancer imaging in recent years. Our aim in this study was to evaluate the relationship and prognostic significance between SUVmax values obtained with Ga-68 PSMA PET/CT and LDH and ALP levels in prostate cancer patients. Methods: We retrospectively evaluated 61 prostate cancer patients who had Ga-68 PSMA PET/CT imaging and who did not have a prostatectomy between 2019 and 2020. PSA, ALP and LDH levels were measured in all patients before or after imaging within a maximum of 28 days. Results: The median age of the patients included in this study was 73 (range: 57-89) and all 61 patients were prostatic adeno-carcinoma. 50 (82%) of the patients had distant metastasis in Ga-68 PSMA PET/CT. There was a significant positive correlation between serum LDH and PSA levels. There was a positive correlation between serum ALP and PSA levels. A negative correlation was found between ALP levels and prostate SUVmax. Conclusions: While negative correlation was found between SUVmax and ALP levels, no correlation was found between LDH levels and SUVmax. High ALP levels were found to be related to metastasis rates and severity and high serum PSA levels.
dc.identifier.doi10.37554/en-j.arch.esp.urol-20210903-3536-35
dc.identifier.endpage558
dc.identifier.issn0004-0614
dc.identifier.issn1576-8260
dc.identifier.issue6
dc.identifier.pmid36138505
dc.identifier.scopus2-s2.0-85138398194
dc.identifier.scopusqualityQ4
dc.identifier.startpage552
dc.identifier.urihttps://doi.org/10.37554/en-j.arch.esp.urol-20210903-3536-35
dc.identifier.urihttps://hdl.handle.net/20.500.12418/28992
dc.identifier.volume75
dc.identifier.wosWOS:000862584200001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherIniestares, S.A.
dc.relation.ispartofArchivos Espanoles De Urologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPSMA
dc.subjectPET
dc.subjectCT
dc.subjectbone metastasis
dc.subjectprostate cancer
dc.subjectalkaline phophatase
dc.subjectlactate dehydrogenase
dc.titleThe Relationship between the SUVmax Value Obtained in Ga-68 PSMA PET/CT and Lactate Dehydrogenase and Alkaline Phosphatase in Prostate Cancer
dc.typeArticle

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