Effect of carnitine on the swimming endurance time in rats

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dc.contributor.authorGuituk, Seth
dc.contributor.authorDemirkazik, Ayse
dc.contributor.authorErdal, Sena
dc.contributor.authorDemir, Tuncer
dc.date.accessioned2024-10-26T18:04:14Z
dc.date.available2024-10-26T18:04:14Z
dc.date.issued2007
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractPurpose: Carnitine plays an important role in lipid metabolism by transporting long-chain fatty acids into the mitochondria for beta-oxidation. The effect of carnitine on exercise capacity is not clear. In this study, effect of carnitine on endurance time in swimming exercise was evaluated in rats. Material and Methods: Two groups were formed and a total of 20 Wistar albino male rats weighing 250-300 g were used in this study. Each rat of experiment group (n = 10) subcutaneous injection of carnitine at the dose of 100 mg/kg/day was made for 20 days, while placebo was given in control group (n = 10). Swimming tests was made in a square shaped glass water tank that was 50 centimeters in height, in width, in depth and filled to a depth of 40 centimeters with 25 +/- 1 degrees C water. The uncoordinated movements and staying under the water for 10 seconds without swimming at the surface were accepted as the exhaustion criteria of the rats. Results: In the rats of experiment group the endurance time increased significantly comparing with the control group (p < 0.05). Conclusion: This result suggests that carnitine may enhance the physical performance. Carnitine might generate that effect by induction of maximal oxygen intake and/or mitocondrial Ca++ sequestration.
dc.identifier.endpage105
dc.identifier.issn2149-2247
dc.identifier.issn2149-2549
dc.identifier.issue2
dc.identifier.scopus2-s2.0-34250694881
dc.identifier.scopusqualityN/A
dc.identifier.startpage101
dc.identifier.urihttps://hdl.handle.net/20.500.12418/28821
dc.identifier.volume29
dc.identifier.wosWOS:000421141000003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherAves
dc.relation.ispartofErciyes Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectExercise test
dc.subjectCarnitine
dc.subjectRats
dc.subjectSwimming
dc.titleEffect of carnitine on the swimming endurance time in rats
dc.typeArticle

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