Associations Between COVID-19 Vaccination Status and Persistent Symptoms: A Prospective Study of Reproductive-Age Women

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dc.contributor.authorCaglayan, Ilkin Seda Can
dc.contributor.authorDemirel, Gulbahtiyar
dc.contributor.authorCan, Ceren Eda
dc.date.accessioned2025-05-04T16:46:52Z
dc.date.available2025-05-04T16:46:52Z
dc.date.issued2025
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: The present study was conducted to determine the relationship between prolonged complaints of women who had COVID-19 infection and whose symptoms persisted and their vaccination status against COVID-19. Methods: This prospective observational study consisted of three groups [The Unvaccinated Group (Control Group: 89), the BioNTech Vaccine Group (114 people), and the Sinovac Vaccine Group (84 people)]. In this study, which included 287 women, prolonged COVID-19 symptoms in their spouses were also questioned. Information was obtained from the participants in the form of questions and answers under outpatient clinical conditions 2 months after their recovery. Women between the ages of 18-45 who had regular menstrual periods in the last 6 months before the pandemic, those whose COVID-19 test was negative and those who received a single dose of vaccine in the vaccinated group were included in the study. Results: The rates of loss of taste and prolonged symptoms of high fever in Sinovac-vaccinated participants were lower than in the other groups in the present study (p < 0.05). A total of 40.5% of those who were vaccinated with Sinovac after COVID-19 had a menstrual cycle length of every 28-40 days, which was higher than the percentage of participants in other groups, and 40.5% of those in this group did not have menstrual pain. Additionally, the menstrual period length of 62.3% of the participants who received the BioNTech vaccine increased (p < 0.05). This increase is higher than the participants in the other group. Conclusion: The study indicated that certain prolonged symptoms of COVID-19 infection were less common among participants vaccinated with Sinovac. In this group, the menstrual cycle length increased, while menstrual pain decreased.
dc.description.sponsorshipThe authors received no specific funding for this work.
dc.description.sponsorshipThe authors would like to thank to women for their involvement in this research. The authors received no specific funding for this work.
dc.identifier.doi10.1111/jep.70005
dc.identifier.issn1356-1294
dc.identifier.issn1365-2753
dc.identifier.issue1
dc.identifier.pmid39918012
dc.identifier.scopus2-s2.0-85216958378
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1111/jep.70005
dc.identifier.urihttps://hdl.handle.net/20.500.12418/35364
dc.identifier.volume31
dc.identifier.wosWOS:001415938400001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofJournal of Evaluation in Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250504
dc.subjectCOVID-19
dc.subjectmenstrual health
dc.subjectprolonged symptoms
dc.subjectvaccine
dc.subjectwomen
dc.titleAssociations Between COVID-19 Vaccination Status and Persistent Symptoms: A Prospective Study of Reproductive-Age Women
dc.typeArticle

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