Untreated meningomyelocele and squamous cell carcinoma: a case report and literature review

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dc.authoridKURT OZKAYA, Nese/0000-0002-0817-1854
dc.contributor.authorKurt-Ozkaya, Nese
dc.date.accessioned2024-10-26T18:03:56Z
dc.date.available2024-10-26T18:03:56Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractBackground Early closure of the meningocele, meningomyelocele, is essential to prevent complications such as hypothermia, infection in the postnatal period. But for some reasons, it is not always possible to repair early. The possibility of malign transformation should be considered in long-term due to nonhealing ulcers and cerebrospinal fluid (CSF) fistula and frequent infections in an adult patient with meningomyelocele. The possibility of conversion to malignancy in the control of an untreated meningomyelocele patient with (CSF) drainage should be especially kept in mind. Case description A case is described of a malignant transformation at the site of a myelomeningocele in a 22-year-old woman. The lumbosacral region was deformed by a large meningomyelocele 10cm in diameter, with areas of scar and ulcer. For 7 years prior to this presentation, the lesion was a large fistula in the roof of the open myelomeningocele. She underwent continuous CSF draining. A biopsy was done which revealed it as squamous cell carcinoma. Conclusion Early closure of meningocele, meningomyelocele is essential to prevent complications such as hypothermia, infection in the postnatal period. Also, especially if there is continuous CSF exposure, the possibility of malignant change should be kept in mind in neglected cases presenting in an adult.
dc.identifier.doi10.1080/02688697.2018.1554178
dc.identifier.endpage600
dc.identifier.issn0268-8697
dc.identifier.issn1360-046X
dc.identifier.issue4
dc.identifier.pmid30652927
dc.identifier.scopus2-s2.0-85164005780
dc.identifier.scopusqualityQ3
dc.identifier.startpage598
dc.identifier.urihttps://doi.org/10.1080/02688697.2018.1554178
dc.identifier.urihttps://hdl.handle.net/20.500.12418/28663
dc.identifier.volume37
dc.identifier.wosWOS:001058780300004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofBritish Journal of Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectSquamous cell carcinoma
dc.subjectmeningomyelocele adult
dc.subjectneural tube defects
dc.subjectchronic wound
dc.subjectcase report
dc.titleUntreated meningomyelocele and squamous cell carcinoma: a case report and literature review
dc.typeReview Article

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