Gender-related differences in presentation and treatment of patients with non-valvular atrial fibrillation: results from RAMSES study

Basit Öğe Kaydı
dc.authoridBASARAN, OZCAN -- 0000-0002-6384-6455en_US
dc.contributor.authorDogan, Volkan
dc.contributor.authorBasaran, Ozcan
dc.contributor.authorBeton, Osman
dc.contributor.authorTekinalp, Mehmet
dc.contributor.authorAykan, Ahmet Cagri
dc.contributor.authorKalaycioglu, Ezgi
dc.contributor.authorBolat, Ismail
dc.contributor.authorTasar, Onur
dc.contributor.authorSafak, Ozgen
dc.contributor.authorKalcik, Macit
dc.contributor.authorKirma, Cevat
dc.contributor.authorBiteker, Murat
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:44:21Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:44:21Z
dc.date.issued2017
dc.department[Dogan, Volkan -- Basaran, Ozcan -- Biteker, Murat] Mugla Sitki Kocman Univ, Dept Cardiol, Fac Med, Mugla, Turkey -- [Beton, Osman] Sivas Cumhuriyet Univ, Dept Cardiol, Fac Med, Sivas, Turkey -- [Tekinalp, Mehmet] Kahramanmaras Necip Fazil State Hosp, Dept Cardiol, Kahramanmaras, Turkey -- [Aykan, Ahmet Cagri -- Kalaycioglu, Ezgi] Trabzon Ahi Evren Chest Cardiovasc Surg Training, Dept Cardiol, Trabzon, Turkey -- [Bolat, Ismail] Fethiye State Hosp, Dept Cardiol, Mugla, Turkey -- [Tasar, Onur] Elazig Training & Res Hosp, Dept Cardiol, Elazig, Turkey -- [Safak, Ozgen] Burdur State Hosp, Dept Cardiol, Burdur, Turkey -- [Kalcik, Macit] Iskilip Atif Hoca State Hosp, Dept Cardiol, Corum, Turkey -- [Kirma, Cevat] Kartal Kosuyolu Heart Training & Res Hosp, Dept Cardiol, Istanbul, Turkeyen_US
dc.description.abstractObjective: Gender is an important feature in the management of atrial fibrillation (AF). This study investigated gender-related differences in patients with AF in Turkey. Methods: As a part of RAMSES (ReAl-life Multicenter Survey Evaluating Stroke prevention strategies in Turkey, NCT02344901) study, information of the patients with AF who successively applied to the hospital was analyzed. This cross-sectional, multi-center, nationwide observational study enrolled 6264 non-valvular AF (NVAF) outpatients (55.9% women) from Turkey. Results: Compared with men, women with NVAF were older (71 years [range: 65-78 years] vs. 70 years [range: 62-77 years]; p<0.001), had lower frequency of coronary artery disease (22.0% vs. 38.3%; p<0.001) and congestive heart failure (18.2% vs. 27.2%; p<0.001). Women had higher median CHA(2)DS(2)-VASc score (4 [range: 3-5] vs. 3 [range: 2-4]; p<0.001), but similar HAS-BLED score (2 [range: 1-2] vs. 2 [range: 1-2]; p=0.141) when compared with men. Anticoagulant therapy use was higher in women (74.5% vs. 69.9%; p<0.001). Analysis of anticoagulation therapy use revealed that 68.5% of men and 61.6% of women (p=0.204) who had low risk for stroke (CHA(2)DS(2)-VASc score: 0 [male], 1 [female]) received anticoagulation therapy, and 30.5% of the men. Meanwhile, 25.3% of the women (p<0.001) with high risk for stroke (CHA(2)DS(2)-VASc score: >= 1 [male], >= 2 [female]) had not received any anticogulant therapy. Conclusion: Although women with NVAF receive better treatment than men, anticoagulation therapy is suboptimal in large proportion of men and women, with underuse in high-risk patients and overuse in low-risk patients. There is an urgent need to improve optimization of anticoagulation in patients with NVAF.en_US
dc.identifier.doi10.5543/tkda.2016.89894en_US
dc.identifier.endpage25en_US
dc.identifier.issn1016-5169
dc.identifier.issue1en_US
dc.identifier.pmid28106016en_US
dc.identifier.scopus2-s2.0-85008465436en_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage16en_US
dc.identifier.urihttps://dx.doi.org/10.5543/tkda.2016.89894
dc.identifier.urihttps://hdl.handle.net/20.500.12418/7034
dc.identifier.volume45en_US
dc.identifier.wosWOS:000396440200005en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTURKISH SOC CARDIOLOGYen_US
dc.relation.ispartofTURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGenderen_US
dc.subjectnon-valvular atrial fibrillationen_US
dc.subjectoral anticoagulan therapyen_US
dc.titleGender-related differences in presentation and treatment of patients with non-valvular atrial fibrillation: results from RAMSES studyen_US
dc.typeArticleen_US

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