Nutraceutical Profiling, Bioactive Composition, and Biological Applications of Lepidium sativum L.

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dc.authoridAlshehri, Mohammed/0000-0002-2041-4695
dc.authoridMartorell, Miquel/0000-0003-3183-7623
dc.authoridHerrera-Bravo, Jesus/0000-0003-0739-7920
dc.authoridTaheri, Yasaman/0000-0002-0836-236X
dc.authoridAlmarhoon, Zainab M./0000-0001-8196-2612
dc.authoridSharifi-Rad, Javad/0000-0002-7301-8151
dc.authoridCalina, Daniela/0000-0002-1523-9116
dc.contributor.authorPainuli, Sakshi
dc.contributor.authorQuispe, Cristina
dc.contributor.authorHerrera-Bravo, Jesus
dc.contributor.authorSemwal, Prabhakar
dc.contributor.authorMartorell, Miquel
dc.contributor.authorAlmarhoon, Zainab M.
dc.contributor.authorSeilkhan, Ainur
dc.date.accessioned2024-10-26T18:11:37Z
dc.date.available2024-10-26T18:11:37Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractThe roots, leaves, and seeds of Lepidium sativum L., popularly known as Garden cress in different regions, have high economic importance; although, the crop is particularly cultivated for the seeds. In traditional medicine, this plant has been reported to possess various biological activities. This review is aimed at providing updated and critical scientific information about the traditional, nutritional, phytochemical, and biological activities of L. sativum. In addition, the geographic distribution is also reviewed. The comprehensive literature search was carried out with the help of different search engines PubMed, Web of Science, and Science Direct. This review highlighted the importance of L. sativum as an edible herb that possesses a wide range of therapeutic properties along with high nutritional values. Preclinical studies (in vitro and in vivo) displayed anticancer, hepatoprotective, antidiabetic, hypoglycemic, antioxidant, antimicrobial, gastrointestinal, and fracture/bone healing activities of L. sativum and support the clinical importance of plant-derived bioactive compounds for the treatment of different diseases. Screening of literature revealed that L. sativum species and their bioactive compounds may be a significant source for new drug compounds and also could be used against malnutrition. Further clinical trials are needed to effectively assess the actual potential of the species and its bioactive compounds.
dc.description.sponsorshipGraphic Era Deemed to be University, Dehradun (Uttarakhand), India
dc.description.sponsorshipAcknowledgments PS thank the Graphic Era Deemed to be University, Dehradun (Uttarakhand), India, for their help and support.
dc.identifier.doi10.1155/2022/2910411
dc.identifier.issn1942-0900
dc.identifier.issn1942-0994
dc.identifier.pmid35096265
dc.identifier.scopus2-s2.0-85123905783
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1155/2022/2910411
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30763
dc.identifier.volume2022
dc.identifier.wosWOS:000829452900001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHindawi Ltd
dc.relation.ispartofOxidative Medicine and Cellular Longevity
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleNutraceutical Profiling, Bioactive Composition, and Biological Applications of Lepidium sativum L.
dc.typeReview Article

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