Recent advances in modified poly (lactic acid) as tissue engineering materials

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dc.authoridSharifi-Rad, Javad/0000-0002-7301-8151
dc.authoridLeyva-Gomez, Gerardo/0000-0002-7940-1100
dc.authoridGonzalez Torres, Maykel/0000-0003-3899-4410
dc.contributor.authorCastaneda-Rodriguez, Samanta
dc.contributor.authorGonzalez-Torres, Maykel
dc.contributor.authorRibas-Aparicio, Rosa Maria
dc.contributor.authorDel Prado-Audelo, Maria Luisa
dc.contributor.authorLeyva-Gomez, Gerardo
dc.contributor.authorGurer, Eda Soenmez
dc.contributor.authorSharifi-Rad, Javad
dc.date.accessioned2024-10-26T18:11:10Z
dc.date.available2024-10-26T18:11:10Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractAs an emerging science, tissue engineering and regenerative medicine focus on developing materials to replace, restore or improve organs or tissues and enhancing the cellular capacity to proliferate, migrate and differentiate into different cell types and specific tissues. Renewable resources have been used to develop new materials, resulting in attempts to produce various environmentally friendly biomaterials. Poly (lactic acid) (PLA) is a biopolymer known to be biodegradable and it is produced from the fermentation of carbohydrates. PLA can be combined with other polymers to produce new biomaterials with suitable physicochemical properties for tissue engineering applications. Here, the advances in modified PLA as tissue engineering materials are discussed in light of its drawbacks, such as biological inertness, low cell adhesion, and low degradation rate, and the efforts conducted to address these challenges toward the design of new enhanced alternative biomaterials.
dc.identifier.doi10.1186/s13036-023-00338-8
dc.identifier.issn1754-1611
dc.identifier.issue1
dc.identifier.pmid36941601
dc.identifier.scopus2-s2.0-85150918564
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1186/s13036-023-00338-8
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30555
dc.identifier.volume17
dc.identifier.wosWOS:000950919800001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBmc
dc.relation.ispartofJournal of Biological Engineering
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiocomposite
dc.subjectBiotechnology
dc.subjectFabrication
dc.subjectNanotechnology
dc.subjectPoly (lactic acid)
dc.subjectTissue Engineering
dc.titleRecent advances in modified poly (lactic acid) as tissue engineering materials
dc.typeReview Article

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