Important Anti-Cancer Applications of Protein Based Nanoparticles

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dc.authoridErgul, Mustafa -- 0000-0003-4303-2996en_US
dc.contributor.authorErgul, Mustafa
dc.contributor.authorErgul, Merve
dc.contributor.authorTutar, Yusuf
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:00:44Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:00:44Z
dc.date.issued2013
dc.department[Ergul, Mustafa -- Tutar, Yusuf] Cumhuriyet Univ, Div Biochem, Fac Pharm, TR-58140 Sivas, Turkey -- [Ergul, Merve] Cumhuriyet Univ, Fac Pharm, Div Pharmacol, TR-58140 Sivas, Turkeyen_US
dc.description.abstractCancer is one of the most important health problems in the world and the treatment approaches are still challenging and generally not at desirable levels. Conventional anti-cancer agents may cause systemic toxicity, have poor solubility, and lack of selectivity. In order to overcome these hurdles, nanoparticle based therapeutics have been widely employed to enhance therapeutic efficacies and reduce systemic toxicity of pharmaceutical agents. In recent years, nanoparticulate carrier systems (NPCs) in medicine have attracted considerable scientific attention and interest in the worldwide because of their unique properties in the diagnosis and therapy of many diseases including cancer. One of the therapeutic strategies of NPCs is protein based nanoparticles. Human serum albumin (HSA) and bovine serum albumin (BSA) are the most frequently used materials for this purpose due to their remarkable advantages. In this review article, we focused on protein based nanoparticles and summarized their important applications including anti-cancer drug delivery, photodynamic therapy, and gene delivery.en_US
dc.identifier.doi10.2174/15701646113106660006en_US
dc.identifier.endpage340en_US
dc.identifier.issn1570-1646
dc.identifier.issn1875-6247
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84894081638en_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage334en_US
dc.identifier.urihttps://dx.doi.org/10.2174/15701646113106660006
dc.identifier.urihttps://hdl.handle.net/20.500.12418/8825
dc.identifier.volume10en_US
dc.identifier.wosWOS:000331099700007en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherBENTHAM SCIENCE PUBL LTDen_US
dc.relation.ispartofCURRENT PROTEOMICSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnti-cancer drug deliveryen_US
dc.subjectbovine serum albuminen_US
dc.subjectgene deliveryen_US
dc.subjecthuman serum albuminen_US
dc.subjectphotodynamic therapyen_US
dc.subjectprotein based nanoparticlesen_US
dc.titleImportant Anti-Cancer Applications of Protein Based Nanoparticlesen_US
dc.typeArticleen_US

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