Measuring the impact: Severity of harm from laboratory errors in 195 tests

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dc.authoridbolat, serkan/0000-0002-8669-8782
dc.authoridzengi, oguzhan/0000-0002-4614-5235
dc.authoridalp, hamit hakan/0000-0002-9202-4944
dc.authoridGulsen, Murat/0000-0003-4494-9536
dc.authoridUcar, Kamil Taha/0000-0002-5875-5954
dc.authoridcihan, murat/0000-0001-6611-7226
dc.authoridOZDEMIR, Habib/0000-0002-1267-7233
dc.contributor.authorCubukcu, Hikmet Can
dc.contributor.authorCihan, Murat
dc.contributor.authorAlp, Hamit Hakan
dc.contributor.authorBolat, Serkan
dc.contributor.authorZengi, Oguzhan
dc.contributor.authorUcar, Kamil Taha
dc.contributor.authorTopcu, Deniz Ilhan
dc.date.accessioned2025-05-04T16:46:53Z
dc.date.available2025-05-04T16:46:53Z
dc.date.issued2024
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjectives This study aimed to objectively assess the potential severity of harm associated with erroneous results in 195 laboratory tests by surveying 514 specialist physicians and medical biochemistry experts.Methods The survey obtained participants' (75 medical biochemists, 439 clinicians) opinions on severity of harm for the erroneous results of 195 tests. The comprehensive list of errors and their effects on test results were obtained from the literature, and then matched with severity of harm scores, from 1 (negligible effect) to 5 (life-threatening injury/death), obtained from the survey responses.Results Participants perceived tests such as cardiac biomarkers, blood gases, coagulation parameters (activated partial thromboplastin time, prothrombin time, international normalized ratio, and dimerized plasmin fragment D), critical ions (potassium, sodium), toxic trace elements (lead, mercury), and specific serum drug levels (lithium, digoxin) to have a greater potential for patient harm in case of errors. Medical biochemistry specialists assigned higher severity scores to some laboratory tests, including total bilirubin, pseudocholinesterase, platelet indices, and some drug levels (cyclosporine, methotrexate, vancomycin).Conclusions A substantial agreement (91%) was observed between medical biochemists and clinicians in terms of the most frequently chosen severity of harm score. The study provided objective severity scores and identified high-risk tests for targeted quality improvement.
dc.identifier.doi10.1093/ajcp/aqae144
dc.identifier.endpage463
dc.identifier.issn0002-9173
dc.identifier.issn1943-7722
dc.identifier.issue3
dc.identifier.pmid39436733
dc.identifier.scopus2-s2.0-105000925353
dc.identifier.scopusqualityQ1
dc.identifier.startpage453
dc.identifier.urihttps://doi.org/10.1093/ajcp/aqae144
dc.identifier.urihttps://hdl.handle.net/20.500.12418/35389
dc.identifier.volume163
dc.identifier.wosWOS:001337823300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherOxford Univ Press Inc
dc.relation.ispartofAmerican Journal of Clinical Pathology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20250504
dc.subjectlaboratory errors
dc.subjectseverity of harm
dc.subjectpatient safety
dc.subjectrisk
dc.subjectrisk management
dc.titleMeasuring the impact: Severity of harm from laboratory errors in 195 tests
dc.typeArticle

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