A novel, green and safe ultrasound-assisted emulsification liquid phase microextraction based on alcohol-based deep eutectic solvent for determination of patulin in fruit juices by spectrophotometry

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dc.contributor.authorAltunay, Nail
dc.contributor.authorElik, Adil
dc.contributor.authorGurkan, Ramazan
dc.date.accessioned2024-10-26T18:03:33Z
dc.date.available2024-10-26T18:03:33Z
dc.date.issued2019
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractIn the study, a novel, green and safe microextraction procedure was developed for the determination and extraction of patulin, alpha,beta-unsaturated lactone (4-hydroxy-4H-furo[3,2-c] pyran-2-(6H)-one), in fruit juice samples by using ultrasound-assisted emulsification liquid phase microextraction based on alcohol-based deep eutectic solvent coupled to micro-volume ultraviolet-visible spectrophotometry. The method is based on formation of chelate complex or nucleophilic adduct formation between patulin and Mg(II) in presence of nucleophilic metal chelating tris-buffer at pH 8.0, and then extraction of the formed complex into the micro-drops of deep eutectic solvent by donor-acceptor mechanism. The optimum conditions for the effective extraction of patulin from fruit juices were 500 mu L of deep eutectic solvent, 75 mu mol L-1 of Mg(II) solution, pH 8.0, ultrasound time of 12 min, respectively. The patulin in enriched phase was detected by micro-volume ultraviolet-visible spectrophotometry at 304 nm. Under optimal conditions, the linear response range of the method was from 7.5 to 420 mu g L-1 with a detection limit of 2.2 mu g L-1. After the validation study, the applicability of the method were tested by analysis of the fruit juice samples. The average recovery for spiked fruit juices was ranged from 90.2% to 106.9%, with relative standard deviations lower than 4.2%.
dc.identifier.doi10.1016/j.jfca.2019.103256
dc.identifier.issn0889-1575
dc.identifier.issn1096-0481
dc.identifier.scopus2-s2.0-85069616035
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.jfca.2019.103256
dc.identifier.urihttps://hdl.handle.net/20.500.12418/28423
dc.identifier.volume82
dc.identifier.wosWOS:000482528800030
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAcademic Press Inc Elsevier Science
dc.relation.ispartofJournal of Food Composition and Analysis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPatulin
dc.subjectDeep eutectic solvents
dc.subjectFruit juices
dc.subjectFood analysis
dc.subjectFood composition
dc.subjectmicroextraction
dc.titleA novel, green and safe ultrasound-assisted emulsification liquid phase microextraction based on alcohol-based deep eutectic solvent for determination of patulin in fruit juices by spectrophotometry
dc.typeArticle

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