Investigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats

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dc.authoridYORUK, MECIT/0000-0001-6820-8105
dc.authoridUslu, Sema/0000-0002-2239-7841
dc.contributor.authorUslu, Sema
dc.contributor.authorCakmak, Gamze
dc.contributor.authorYoruk, Mecit
dc.date.accessioned2024-10-26T18:04:14Z
dc.date.available2024-10-26T18:04:14Z
dc.date.issued2019
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractThis study was planned to determine the histochemical alterations of the submandibular gland by implantation of long-term GnRH (deslorelin 4.7 mg). Eighteen Wistar albino rats were used in the study. Alcian blue (AB; pH: 2.5), periodic acid-Schiff (PAS) staining was performed to determine the microscopic structure and histochemical structure of the GI submandibular gland. The Avidin-Biotin Complex (ABC) method was used to determine the immunohistochemical reactivity of lectin. After GnRH implantation, the organs were examined and atrophies were observed in organs. In the group in which the implants were removed, it was determined that there was no atrophy; organ structures and microscopic examination were similar to the control group. At the end of the study, submandibular gland was fixed in 10 % buffered formaldehyde. In three groups, PAS and AB histochemical staining revealed similar reactions. Immunohistochemically, lectin activity was found to react positively.
dc.identifier.doi10.4067/S0717-95022019000301008
dc.identifier.endpage1015
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85069813835
dc.identifier.scopusqualityQ3
dc.identifier.startpage1008
dc.identifier.urihttps://doi.org/10.4067/S0717-95022019000301008
dc.identifier.urihttps://hdl.handle.net/20.500.12418/28820
dc.identifier.volume37
dc.identifier.wosWOS:000476478000036
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSoc Chilena Anatomia
dc.relation.ispartofInternational Journal of Morphology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSubmandibular gland
dc.subjectGnRH
dc.subjectHistochemistry
dc.subjectLectin
dc.subjectRat
dc.titleInvestigation of the Effect of GnRH (Deslorelin) on the Histochemical Structure of Salivary Glands in Rats
dc.typeArticle

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