The Role of Systemic Immune Inflammation Index for Predicting Saphenous Vein Graft Disease in Patients with Coronary Artery Bypass Grafting

dc.authoridYildirim, Arafat/0000-0002-2798-7488
dc.authoridYAVUZ, FETHI/0000-0003-1913-4212
dc.authoridDOGDUS, Mustafa/0000-0002-3895-1923
dc.authoridDINDAS, FERHAT/0000-0003-0053-9594
dc.authoridKilic, Salih/0000-0002-3579-3747
dc.authoridYenercag, Mustafa/0000-0002-0933-7852
dc.contributor.authorDogdus, Mustafa
dc.contributor.authorDindas, Ferhat
dc.contributor.authorYenercag, Mustafa
dc.contributor.authorYildirim, Arafat
dc.contributor.authorAbacioglu, Ozge Ozcan
dc.contributor.authorKilic, Salih
dc.contributor.authorYavuz, Fethi
dc.date.accessioned2024-10-26T18:11:21Z
dc.date.available2024-10-26T18:11:21Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractAs inflammation plays a significant role in the development of coronary artery disease, we hypothesized that there may be a relation between the systemic immune inflammation index (SII) and saphenous vein graft disease (SVGD). The study population consisted of 716 consecutive patients who underwent elective coronary angiography (CAG) >1 year after bypass grafting. The patients were divided into 2 groups depending on the extent of SVG patency. SII value was significantly higher in the SVGD(+) group compared with the SVGD(-) group (P < .001). In multivariate logistic regression analysis, SII (P < .001, odds ratio (OR) = 3.27, 95% CI = 1.94-5.65) and neutrophil-to-lymphocyte ratio (NLR) (P < .001, OR = 2.08, 95% CI = 1.59-3.11) were found to be independent predictors of SVGD. An SII value of >935 (x10(3)/ml) has 89.2% sensitivity and 70.6% specificity for the prediction of the SVGD, and an NLR value of >4.15 has 54.6% sensitivity and 68.5% specificity for the prediction of the SVGD. The AUC of SII was found to be greater than the AUC of NLR (P = .002), platelet-to-lymphocyte ratio (PLR) (P = .009), lymphocyte-to-monocyte ratio (LMR) (P = .013), MPV (P = .011), and C-reactive protein (CRP) (P = .034) in predicting SVGD. In conclusion, we demonstrated that SII, which is among the new inflammation indexes, is a more reliable predictor in determining SVGD than the NLR, PLR, and LMR.
dc.identifier.doi10.1177/00033197221129356
dc.identifier.endpage586
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue6
dc.identifier.pmid36154493
dc.identifier.scopus2-s2.0-85139132465
dc.identifier.scopusqualityQ2
dc.identifier.startpage579
dc.identifier.urihttps://doi.org/10.1177/00033197221129356
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30637
dc.identifier.volume74
dc.identifier.wosWOS:000859264100001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Inc
dc.relation.ispartofAngiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectsystemic immune inflammation index
dc.subjectneutrophil-to-lymphocyte ratio
dc.subjectplatelet-to-lymphocyte ratio
dc.subjectlymphocyte-to-monocyte ratio
dc.subjectsaphenous vein graft disease
dc.titleThe Role of Systemic Immune Inflammation Index for Predicting Saphenous Vein Graft Disease in Patients with Coronary Artery Bypass Grafting
dc.typeArticle

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