Effects of Triclosan-Impregnated Suture Materials on Colonic Anastomosis

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dc.contributor.authorAtabey, Mustafa
dc.contributor.authorTas, Ayca
dc.contributor.authorTopcu, Omer
dc.contributor.authorSilig, Yavuz
dc.date.accessioned2024-10-26T18:00:11Z
dc.date.available2024-10-26T18:00:11Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: Symptomatic anastomotic leakage observed after colorectal surgery is one of the major complications. One of the factors affecting the anastomosis healing is the type of suture material used. This study aims to investigate the effects of the suture material polydioxanone (PDS, Ethicon), which is late absorbable and has a monofilament structure, and the suture material polyglactin 910 (Vicryl, Ethicon), which is absorbable and has a multifilament structure, on the healing of colonic anastomosis, and to compare the traditional forms of these sutures with their antibacterial effective triclosan-impregnated forms (PDS Plus, Ethicon and Vicryl Plus, Ethicon). Materials and Methods: The rats were divided into four equal groups consisting of 10 subjects each: Group I: Vicryl; Group II: Vicryl Plus; Group III: PDS; and Group IV: PDS Plus. The presence of wound infection, whether the integrity of the abdominal wall was maintained, intra-abdominal adhesion scoring, the presence of intra-abdominal abscess, and whether the macroscopic integrity of anastomosis was maintained were evaluated. Results: According to the results of this experimental study, while the highest ABP and hydroxyproline levels were observed in the PDS Plus group, the lowest values were observed in the Vicryl group. However, the difference was not statistically significant. Conclusion: Slowly absorbable and monofilament PDS suture material causes less tissue reaction and inflammatory response compared to the Vicryl suture material that is absorbable in the colonic anastomosis line and multifilament.
dc.description.sponsorshipSivas Cumhuriyet University (Sivas, Turkey) [CUBAP T-562]
dc.description.sponsorshipThe current study was funded by Sivas Cumhuriyet University (Sivas, Turkey) via research grants (grant no. CUBAP T-562) provided to the project.
dc.identifier.doi10.14744/etd.2019.70973
dc.identifier.endpage17
dc.identifier.issn2149-2247
dc.identifier.issn2149-2549
dc.identifier.issue1
dc.identifier.startpage12
dc.identifier.trdizinid380495
dc.identifier.urihttps://doi.org/10.14744/etd.2019.70973
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/380495
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27567
dc.identifier.volume42
dc.identifier.wosWOS:000516725700004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherErciyes Univ Sch Medicine
dc.relation.ispartofErciyes Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPolydioxanone
dc.subjectpolyglactin 910
dc.subjecttriclosan
dc.subjectcolonic anastomosis
dc.subjecthydroxyproline
dc.titleEffects of Triclosan-Impregnated Suture Materials on Colonic Anastomosis
dc.typeArticle

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