Investigation of Effects of Essential Oil from Berries of Juniperus excelsa Bieb. Subsp excelsa (Cupressaceae) on Angiogenesis in Shell-less Chick Embryo (CAM) Culture

dc.contributor.authorGoze, Aysegul
dc.contributor.authorGose, Ismihan
dc.contributor.authorAlim, Ahmet
dc.contributor.authorSaygin, Huseyin
dc.contributor.authorAlim, Betul Aycan
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:47:46Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:47:46Z
dc.date.issued2015
dc.department[Goze, Aysegul] Cumhuriyet Univ, Dept Prosthet Dent Treatment, Fac Dent, TR-58140 Sivas, Turkey -- [Gose, Ismihan] Cumhuriyet Univ, Vocat Sch Hlth Serv, TR-58140 Sivas, Turkey -- [Alim, Ahmet] Cumhuriyet Univ, Dept Pharmaceut Microbiol, Fac Pharm, TR-58140 Sivas, Turkey -- [Saygin, Huseyin] Cumhuriyet Univ, Fac Med, Dept Urol, TR-58140 Sivas, Turkey -- [Alim, Betul Aycan] Marmara Univ, Dept Endodont, Fac Dent, TR-34365 Istanbul, Turkeyen_US
dc.description.abstractThe aim of this study was to investigate the effect of essential oil of the berries from Juniperus excelsa Bieb. subsp. excelsa (Cupressaceae) to the vascularization systems of the chick embryos in a chorioallantoic membrane model. The berries of J. excelsa were subjected to hydrodistillation. 50 mu l of essential oil were applied to the center of the blastodisc using a precision micropipette prior to the transfer of shell-less cultures to the incubator. Antiangiogenic effect of essential oil of the study plant was determined with the use of the chick chorioallantoic membrane model. Numbers of main, branching and capillary blood vessels were counted. In the statistical analysis, when the groups were compared with regard to the main blood vessel (MBV) and branch blood vessel (BBV) development, no significant difference (p>0.05) was observed. However, when the groups were compared with regard to capillary vessel (CV) development, the difference between the data of the groups was found significant (p<0.05). This study examined the effect of exposure J. excelsa essential oil on extraembryonic vascular development in the chick embryo area vasculosa (AV) in shell-less culture for the first time. Essential oil of the berries from J. excelsa has antiangiogenic effect.en_US
dc.identifier.doi10.1080/0972060X.2014.971060en_US
dc.identifier.endpage1107en_US
dc.identifier.issn0972-060X
dc.identifier.issn0976-5026
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-84944686087en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage1100en_US
dc.identifier.urihttps://dx.doi.org/10.1080/0972060X.2014.971060
dc.identifier.urihttps://hdl.handle.net/20.500.12418/7721
dc.identifier.volume18en_US
dc.identifier.wosWOS:000363292800008en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofJOURNAL OF ESSENTIAL OIL BEARING PLANTSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngiogenesisen_US
dc.subjectEssential oilen_US
dc.subjectJuniperus excelsaen_US
dc.subjectShell-less chick embryo cultureen_US
dc.titleInvestigation of Effects of Essential Oil from Berries of Juniperus excelsa Bieb. Subsp excelsa (Cupressaceae) on Angiogenesis in Shell-less Chick Embryo (CAM) Cultureen_US
dc.typeArticleen_US

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