Insulin and Heparin Therapies in Acute Pancreatitis due to Hypertriglyceridemia

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dc.contributor.authorAltinkaya, Engin
dc.contributor.authorAktas, Ahmet
dc.date.accessioned2024-10-26T18:05:51Z
dc.date.available2024-10-26T18:05:51Z
dc.date.issued2021
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: To compare insulin infusion and heparin infusion, used to treat hypertriglyceridemia-induced acute pancreatitis in terms of efficacy. Study Design: Descriptive study. Place and Duration of Study: Department of Gastroenterology, Division of Internal Disease, Sivas Cumhuriyet University Hospital, Sivas, Turkey, from 1st January 2013 to 1st January 2020. Methodology: Patients who presented with abdominal pain and were found to have edematous pancreatitis on computed tomography imaging were retrospectively reviewed. Thirty-six patients with hypertriglyceridemia were included. Eighteen of the patients were given insulin infusion, while the other 18 were given heparin infusion therapy. The patients' gender, age, admission amylase values, AST, ALT, total cholesterol, glucose, lactate dehydrogenase (LDH), CRP, leukocyte, pre-treatment and post-treatment first, second, and third-day triglyceride levels were recorded from the files. Results: The post-treatment third-day triglyceride levels of the insulin therapy group were statistically significantly lower compared to the heparin therapy group (432.5; 984, p<0.001, respectively). Conclusion: Insulin infusion, in addition to fluid therapy and electrolyte imbalance, was more effective than heparin therapy in patients with hypertriglyceridemia-induced acute pancreatitis.
dc.identifier.doi10.29271/jcpsp.2021.11.1337
dc.identifier.endpage1340
dc.identifier.issn1022-386X
dc.identifier.issn1681-7168
dc.identifier.issue11
dc.identifier.pmid34689493
dc.identifier.scopus2-s2.0-85117946514
dc.identifier.scopusqualityQ3
dc.identifier.startpage1337
dc.identifier.urihttps://doi.org/10.29271/jcpsp.2021.11.1337
dc.identifier.urihttps://hdl.handle.net/20.500.12418/29230
dc.identifier.volume31
dc.identifier.wosWOS:000711314600015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherColl Physicians & Surgeons Pakistan
dc.relation.ispartofJcpsp-Journal of the College of Physicians and Surgeons Pakistan
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHypertriglyceridemia-induced acute pancreatitis
dc.subjectInsulin therapy
dc.subjectHeparin therapy
dc.titleInsulin and Heparin Therapies in Acute Pancreatitis due to Hypertriglyceridemia
dc.typeArticle

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