Evaluation of the Demographic and Laboratory Data of Patients Diagnosed with Crimean-Congo Hemorrhagic Fever in the Emergency Department and Their Relationship with Morbidity and Mortality

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dc.authoridDEMIRTAS, ERDAL/0000-0003-0853-0623
dc.authoridYurtbay, Sefa/0000-0002-7373-1002
dc.authoridTEKIN, Yusuf Kenan/0000-0001-8047-4836
dc.authoridBUYUKTUNA, SEYIT ALI/0000-0001-6518-7361
dc.contributor.authorSoylu, Umit
dc.contributor.authorDemirtas, Erdal
dc.contributor.authorBuyuktuna, Seyit Ali
dc.contributor.authorKorkmaz, Ilhan
dc.contributor.authorTekin, Yusuf Kenan
dc.contributor.authorYurtbay, Sefa
dc.date.accessioned2024-10-26T18:00:15Z
dc.date.available2024-10-26T18:00:15Z
dc.date.issued2021
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractAim: Crimean-Congo hemorrhagic fever (CCHF) is transmitted by infected ticks or through contaminated blood, tissue, and body fluids. Pathological laboratory results, such as thrombocytopenia, leukopenia, and anemia, along with biochemistry and coagulation parameters, can be used for its diagnosis and the determination of its prognosis. Materials and Methods: Data of patients over 17 years of age diagnosed with CCHF between 2013 and 2018 were reviewed retrospectively. The complete blood count, liver-renal enzymes, electrolytes, prothrombin time, activated partial thromboplastin time (aPTT), D-dimer values, fibrinogen values, and international normalized ratio (INR) were recorded and analyzed at admission. Results: Non-survivors had higher levels of alkaline phosphatase, alanine aminotransferase, amylase, aspartate aminotransferase (AST), blood urea nitrogen (BUN), direct bilirubin, gamma-glutamyl transferase, creatinine, potassium, total bilirubin and uric acid (p<0.05), whereas creatine kinase (CK), CK-MB, and calcium levels were lower (p<0.05). Non-survivors had higher levels of basophil, mean corpuscular hemoglobin concentration, mean corpuscular volume, neutrophil, nucleated red blood cells, platelet distribution width, and white blood cells (p<0.05). Conclusion: Evaluation of routine blood parameters of CCHF patients in the emergency room is a useful tool to accelerate recovery in intensive care and prevent delay in patient treatment. Platelet, aPTT, INR, BUN, and AST values are predictors for mortality.
dc.identifier.doi10.4274/eajem.galenos.2020.37039
dc.identifier.endpage18
dc.identifier.issn2149-5807
dc.identifier.issn2149-6048
dc.identifier.issue1
dc.identifier.startpage12
dc.identifier.trdizinid407071
dc.identifier.urihttps://doi.org/10.4274/eajem.galenos.2020.37039
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/407071
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27594
dc.identifier.volume20
dc.identifier.wosWOS:000644873000003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherEmergency Medicine Physicians Assoc Turkey
dc.relation.ispartofEurasian Journal of Emergency Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCrimean-Congo hemorrhagic fever
dc.subjectwhite blood cell
dc.subjectthrombocyte
dc.subjectmortality
dc.titleEvaluation of the Demographic and Laboratory Data of Patients Diagnosed with Crimean-Congo Hemorrhagic Fever in the Emergency Department and Their Relationship with Morbidity and Mortality
dc.typeArticle

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