A new perspective to determine the severity of cases with Crimean-Congo hemorrhagic fever

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dc.authoridElaldi, Nazif -- 0000-0002-9515-770Xen_US
dc.contributor.authorBakir, Mehmet
dc.contributor.authorEngin, Aynur
dc.contributor.authorGozel, Mustafa Gokhan
dc.contributor.authorElaldi, Nazif
dc.contributor.authorKilickap, Saadettin
dc.contributor.authorCinar, Ziynet
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:03:38Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:03:38Z
dc.date.issued2012
dc.department[Bakir, Mehmet -- Engin, Aynur -- Gozel, Mustafa Gokhan -- Elaldi, Nazif] Cumhuriyet Univ, Dept Infect Dis & Clin Microbiol, Sch Med, TR-58140 Sivas, Turkey -- [Kilickap, Saadettin] Cumhuriyet Univ, Dept Med Oncol, TR-58140 Sivas, Turkey -- [Cinar, Ziynet] Cumhuriyet Univ, Dept Biostat, TR-58140 Sivas, Turkeyen_US
dc.description.abstractBackground & objectives: We have established a severity grading score (SOS) system for predicting the fatality :in Crimean-Congo hemorrhagic fever (CCHF) for the first time. Methods: This SOS has been set up by using several variables which were assumed to be associated with mortality according to the literature and also were considered to have clinical importance. Results: In all, 237 patients who had symptoms of CCHF for <= 5 days were included. The patients were grouped into three categories according to the mortality risk by using SOS as follows : low or no risk, intermediate and high risk groups. A SOS <= 5 showed no association with mortality (there were 158 cases in this group and all survived). This group constituted 66.7% of all the patients with CCHF. A SOS 6-10 showed moderate risk of mortality (10%) and seven out of 70 patients in this group died. SOS >= 11 means high risk for mortality (67%) and six out of 9 patients in this group died (p = 0.001). The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for >= 11 points of SOS were 67, 100, 98, 100, and 98%, respectively. Conclusions: This scoring system may help the clinicians to decide which patient to refer to a tertiary step hospital which may also decrease the cost and improve the functionality of healthcare staff.en_US
dc.identifier.endpage110en_US
dc.identifier.issn0972-9062
dc.identifier.issue2en_US
dc.identifier.pmid22898483en_US
dc.identifier.scopus2-s2.0-84864382432en_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage105en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12418/9101
dc.identifier.volume49en_US
dc.identifier.wosWOS:000308519200009en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMALARIA RESEARCH CENTRE, INDIAN COUNCIL MEDICAL RESEARCH-ICMRen_US
dc.relation.ispartofJOURNAL OF VECTOR BORNE DISEASESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCrimean-Congo hemorrhagic feveren_US
dc.subjectmortalityen_US
dc.subjectseverity grading scoreen_US
dc.titleA new perspective to determine the severity of cases with Crimean-Congo hemorrhagic feveren_US
dc.typeArticleen_US

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