Investigation of Metabolic Syndrome Frequency and Subclinical Hypothyroidism in Obese Children and Adolescents: A Retrospective Single Center Observational Study

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dc.contributor.authorBeysel, Perihan
dc.contributor.authorÇelik, Nurullah
dc.date.accessioned2024-10-26T17:51:19Z
dc.date.available2024-10-26T17:51:19Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: The prevalence of obesity, as an important public health problem, has been raised in our country as well as all over the world. There is insufficient data in terms of metabolic syndrome (MS) prevalence and its risk factors in Turkey. The aim of this study is to determine the frequency and risk factors of MS in 6-18 years old obese children and adolescents, to compare thyroid function test results, and to calculate the frequency of sub clinical hypothyroidism in patients with and without MS. Material and Methods: This retrospective single-center observational study was conducted on 957 obese children and adolescents aged 6-18 years. The cases were divided into 2 groups as 6-12 years old (Group 1) and 12-18 years old (Group 2). Than, the frequencies of MS were calculated according to the criteria of the International Diabetes Federation (IDF), Cook et al. and de Ferranti et al. Thyroid function test (thyroid-stimulating hormone and free T4) results were compared in patients with and without MS. Results: The prevalence of MS in Group 1 and Group 2 were found as 7.7% and 12.5%, respectively for IDF criteria, 12.9% and 26.4% for Cook criteria, and 25 and 37.4% for de Ferranti criteria. In Group 2, obese girls had lower free T4 levels than boys (p=0.04). The frequency of subclinical hypothyroidism was similar in the groups with and without MS (p>0.05). Conclusion: In this study, the frequency of MS according to different diagnostic criteria varied, similar to previous studies in our country. So it is necessary to develop an internationally acceptable MS diagnostic criterion in childhood age group. © 2022 OrtadogŸu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S.. All rights reserved.
dc.identifier.doi10.5336/pediatr.2021-83667
dc.identifier.endpage18
dc.identifier.issn1300-0381
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85125454687
dc.identifier.scopusqualityQ4
dc.identifier.startpage9
dc.identifier.trdizinid515404
dc.identifier.urihttps://doi.org/10.5336/pediatr.2021-83667
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/515404
dc.identifier.urihttps://hdl.handle.net/20.500.12418/26166
dc.identifier.volume31
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isotr
dc.publisherOrtadogŸu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S.
dc.relation.ispartofTurkiye Klinikleri Pediatri
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMetabolic syndrome; Pediatric obesity; Prevalence; Thyroid hormones
dc.titleInvestigation of Metabolic Syndrome Frequency and Subclinical Hypothyroidism in Obese Children and Adolescents: A Retrospective Single Center Observational Study
dc.title.alternativeObez Çocuk ve Ergenlerde Metabolik Sendrom Sikli?i ve Subklinik Hipotiroidinin Araştirilmasi: Retrospektif Tek Merkezli Gözlemsel Bir Çalişma
dc.typeArticle

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