Ydj1 but not Sis1 stabilizes Hsp70 protein under prolonged stress in vitro

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dc.contributor.authorTutar, Lutfi
dc.contributor.authorTutar, Yusuf
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:15:29Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:15:29Z
dc.date.issued2008
dc.departmentCumhuriyet Univ, Fac Sci, Dept Biochem & Chem, TR-58140 Sivas, Turkeyen_US
dc.description.abstractYeast cytosol has two important co-chaperons; Ydj1 and Sis1. Genetic experiments showed that Ydj1 is not I essential for viability; however, cells lacking it grow very poorly at 30 degrees C or unable to grow at extreme temperatures. On the other hand, Sis1 is an essential protein and apparently plays a functional role at assembly or disassembly of protein complexes. Stability experiments revealed that only Ydj1-protected Hsp70 proteins can hydrolyze ATP under prolonged stress. (c) 2007 Wiley Periodicals, Inc.en_US
dc.identifier.doi10.1002/bip.20881en_US
dc.identifier.endpage174en_US
dc.identifier.issn0006-3525
dc.identifier.issue3en_US
dc.identifier.pmid17985367en_US
dc.identifier.scopus2-s2.0-38949188609en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage171en_US
dc.identifier.urihttps://dx.doi.org/10.1002/bip.20881
dc.identifier.urihttps://hdl.handle.net/20.500.12418/10415
dc.identifier.volume89en_US
dc.identifier.wosWOS:000253245900001en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJOHN WILEY & SONS INCen_US
dc.relation.ispartofBIOPOLYMERSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectstabilityen_US
dc.subjectHsp70en_US
dc.subjectYdj1en_US
dc.subjectSis1en_US
dc.titleYdj1 but not Sis1 stabilizes Hsp70 protein under prolonged stress in vitroen_US
dc.typeArticleen_US

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