Phytochemical screening and evaluation of antioxidant, enzyme inhibition, anti-proliferative and calcium oxalate anti-crystallization activities of Micromeria fruticosa spp. brachycalyx and Rhus coriaria

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dc.authoridtaskin, turgut/0000-0001-8475-6478
dc.authoridYILMAZ, Beyza Nur/0000-0002-4418-3182
dc.contributor.authorTaskin, Turgut
dc.contributor.authorDogan, Murat
dc.contributor.authorYilmaz, Beyza Nur
dc.contributor.authorSenkardes, Ismail
dc.date.accessioned2024-10-26T18:05:55Z
dc.date.available2024-10-26T18:05:55Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractMicromeria fruticosa spp. brachycalyx species (Lamiaceae) is used as a spice and flavoring agent. Rhus coriaria (Sumac) is widely used both spice and medicinally. In this study, antioxidant, anti-urease, anticholinesterase, anti-proliferative and calcium oxalate anti-crystallization activities of different extracts from M. fruticosa spp. brachycalyx aerial parts and R. coriaria leaves were investigated. Besides, the phytochemical content of these species was analyzed qualitatively and quantitatively. R. coriaria methanol extract showed stronger antioxidant (DPPH, FRAP, CUPRAC, ARTS) and anticholinesterase (46.85%) activity than M. fruticosa spp. brachycalyx extracts. M. fruticosa spp. brachycalyx methanol extract was found to have the highest anti-urease (11.39%) and anti-proliferative (MCF-7: 53.51%) potential. It was observed that the methanol extracts of both plants had a significant inhibition effect on calcium oxalate crystallization. R. coriaria methanol extract was determined to contain high amounts of total flavonoids (0.177 mgQE/mg extract) and tannins (0.365 mg TAE/mg extract) contents. The extracts from both plants have no cytotoxic effects on the healthy cell (L-929) and have strong biological activities in parallel with traditional use, suggesting that these plants may be used as natural sources in the future.
dc.description.sponsorshipScientific and Technological Research Council of Turkey [2209/A, 1919B011904109]
dc.description.sponsorshipThis study was supported by The Scientific and Technological Research Council of Turkey (2209/A, Project no: 1919B011904109).
dc.identifier.doi10.1016/j.bcab.2020.101670
dc.identifier.issn1878-8181
dc.identifier.scopus2-s2.0-85098845257
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.bcab.2020.101670
dc.identifier.urihttps://hdl.handle.net/20.500.12418/29262
dc.identifier.volume27
dc.identifier.wosWOS:000561869500007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofBiocatalysis and Agricultural Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectM. fruticosa spp. brachycalyx
dc.subjectR.coriaria
dc.subjectPhytochemical contents
dc.subjectBiological activity
dc.titlePhytochemical screening and evaluation of antioxidant, enzyme inhibition, anti-proliferative and calcium oxalate anti-crystallization activities of Micromeria fruticosa spp. brachycalyx and Rhus coriaria
dc.typeArticle

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