A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris

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dc.contributor.authorKozan, Ahmet
dc.contributor.authorGuner, Rukiye Yasak
dc.contributor.authorAkyol, Melih
dc.date.accessioned2024-10-26T18:08:00Z
dc.date.available2024-10-26T18:08:00Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractAcne vulgaris is a chronic inflammatory skin disease that mostly develops during adolescence and continues throughout adulthood. It affects the face, the main location of cosmetic appearance. Despite many developments in acne treatment, various combination therapies are needed to create the best option. Ninety patients were included in this study. We used the global acne grading system (GAGS) and the lesion counting and photographic standards that were used by Hayashi et al., to assess acne severity. The patients were randomly divided into three groups as group 1 (using only 5% BPO, twice a day), group 2 (using only the combination of 5% BPO + 3% erythromycin, twice a day), and group 3 (using only the combination of 4% niacinamide + 1% gallic acid + 1% lauric acid, twice a day). Thirty patients were included in each group. The scores were evaluated at weeks 0, 2, 4 and 8, and compared with each other. As a result of the study, all three treatment types were found to be effective. The combination of 4% niacinamide + 1% gallic acid + 1% lauric acid can be used as an alternative topical treatment for acne vulgaris to prevent resistance against topical antibiotics and the side effects of some other treatments.
dc.identifier.doi10.1111/dth.13534
dc.identifier.issn1396-0296
dc.identifier.issn1529-8019
dc.identifier.issue4
dc.identifier.pmid32390309
dc.identifier.scopus2-s2.0-85087173559
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1111/dth.13534
dc.identifier.urihttps://hdl.handle.net/20.500.12418/29768
dc.identifier.volume33
dc.identifier.wosWOS:000542806000001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofDermatologic Therapy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectacne
dc.subjectgallic acid
dc.subjectlauric acid
dc.subjectniacinamide
dc.subjecttreatment
dc.titleA retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris
dc.typeArticle

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