Phytochemicals, antioxidant, and antityrosinase activities of Achillea sivasica Celik and Akpulat

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dc.authoridOzek, Temel -- 0000-0003-4251-8783en_US
dc.contributor.authorHaliloglu, Yesim
dc.contributor.authorOzek, Temel
dc.contributor.authorTekin, Mehmet
dc.contributor.authorGoger, Fatih
dc.contributor.authorBaser, Kemal Husnu Can
dc.contributor.authorOzek, Gulmira
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:44:07Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:44:07Z
dc.date.issued2017
dc.department[Haliloglu, Yesim -- Ozek, Temel -- Goger, Fatih -- Ozek, Gulmira] Anadolu Univ, Dept Pharmacognosy, Fac Pharm, TR-26470 Eskisehir, Turkey -- [Tekin, Mehmet] Cumhuriyet Univ, Dept Pharmaceut Bot, Fac Pharm, Sivas, Turkey -- [Baser, Kemal Husnu Can] Near East Univ, Dept Pharmacognosy, Fac Pharm, Nicosia, N Cyprus, Turkeyen_US
dc.description.abstractThe present study is the first report on essential oil (EO) composition, phytochemicals, and biological potential of Achillea sivasica tested against free radicals, oxidative damage, and tyrosinase enzyme. Gas-Chromatography Flame Ionization Detector (GC-FID) and gas chromatography/mass spectrometry (GC/MS) analyses revealed that beta-pinene (11.5%, 9.3%, and 6.7%), beta-pinene (7.0%, 3.0%, and 6.9%), 1,8-cineole (18.0%, 22.1%, and 6.7%), and camphor (7.6%, 4.1%, and 9.0%) were the major constituents in the EOs from the herb, flower, and leaves, respectively. Liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) analysis of the extracts revealed the presence of caffeoylquinic acid derivatives, luteolin, apigenin, patuletin, isorhamnetin, cirsimaritin, and santin. The leaf extracts demonstrated strongest free radical scavenging, cupric reducing, lipid peroxidation inhibition, and antityrosinase activities.en_US
dc.description.sponsorshipAnadolu University Scientific Research Department [1504S163]en_US
dc.description.sponsorshipThe authors are gratefully thanks to Anadolu University Scientific Research Department for supporting this research project (BAP No 1504S163). All authors of the manuscript declare that they do not have financial/ commercial conflicts of interest.en_US
dc.identifier.doi10.1080/10942912.2017.1308954en_US
dc.identifier.endpageS706en_US
dc.identifier.issn1094-2912
dc.identifier.issn1532-2386
dc.identifier.scopus2-s2.0-85022214293en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpageS693en_US
dc.identifier.urihttps://dx.doi.org/10.1080/10942912.2017.1308954
dc.identifier.urihttps://hdl.handle.net/20.500.12418/6921
dc.identifier.volume20en_US
dc.identifier.wosWOS:000423507200060en_US
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS INCen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF FOOD PROPERTIESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAchillea sivasicaen_US
dc.subjectAntioxidanten_US
dc.subjectEssential oilen_US
dc.subjectExtracten_US
dc.subjectTyrosinaseen_US
dc.titlePhytochemicals, antioxidant, and antityrosinase activities of Achillea sivasica Celik and Akpulaten_US
dc.typeArticleen_US

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