Evaluation of Serum Glucagon-Like Peptide 1 and Vitamin D Levels in Elderly Patients with Bone Fractures

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dc.contributor.authorPazarci, Ozhan
dc.contributor.authorDogan, Halef Okan
dc.contributor.authorKilinc, Seyran
dc.contributor.authorCamurcu, Yalkin
dc.date.accessioned2024-10-26T18:08:05Z
dc.date.available2024-10-26T18:08:05Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjectives: To evaluate the correlation between levels of serum vitamin D and glucagon-like peptide-1 (GLP-1) in elderly patients with bone fractures. Materials and Methods: This study included 56 patients and 31 control subjects. The patients included were those aged >= 65 years who were admitted to our hospital with a diagnosis of bone fracture. The control group comprised age-matched, healthy individuals. Levels of serum vitamin D and GLP-1 were measured and compared between the 2 groups. Results: Significant differences were noted between the groups in terms of serum levels of vitamin D (p < 0.001) and serum levels of GLP-1 (p < 0.001). A positive correlation was observed between serum levels of vitamin D and GLP-1. Conclusion: Serum levels of GLP-1 were found to be significantly lower in elderly patients with bone fracture compared to healthy adults. In addition, a significant correlation was found between decreased vitamin D and GLP-1 levels. These results may therefore demonstrate the protective effects of GLP-1 on bone structure and metabolism, similar to those of vitamin D.
dc.description.sponsorshipScientific Research Project Fund of Cumhuriyet University
dc.description.sponsorshipThis work was supported by the Scientific Research Project Fund of Cumhuriyet University (project No. T724).
dc.identifier.doi10.1159/000502132
dc.identifier.endpage224
dc.identifier.issn1011-7571
dc.identifier.issn1423-0151
dc.identifier.issue3
dc.identifier.pmid31311025
dc.identifier.scopus2-s2.0-85085715018
dc.identifier.scopusqualityQ2
dc.identifier.startpage219
dc.identifier.urihttps://doi.org/10.1159/000502132
dc.identifier.urihttps://hdl.handle.net/20.500.12418/29792
dc.identifier.volume29
dc.identifier.wosWOS:000605967300003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofMedical Principles and Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectVitamin D
dc.subjectBone
dc.subjectFracture
dc.subjectElderly patients
dc.subjectGlucagon-like peptide-1
dc.titleEvaluation of Serum Glucagon-Like Peptide 1 and Vitamin D Levels in Elderly Patients with Bone Fractures
dc.typeArticle

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