The significance of taurine for patients with Crimean-Congo hemorrhagic fever and COVID-19 diseases: a cross-sectional study

Basit Öğe Kaydı
dc.authoridTEKIN, Yusuf Kenan/0000-0001-8047-4836
dc.authoridAydin, Huseyin/0000-0002-3194-830X
dc.authoridYurtbay, Sefa/0000-0002-7373-1002
dc.contributor.authorCelik, Simsek
dc.contributor.authorAydin, Huseyin
dc.contributor.authorTekin, Yusuf Kenan
dc.contributor.authorErtemur, Zeynep
dc.contributor.authorKorkmaz, Ilhan
dc.contributor.authorYurtbay, Sefa
dc.contributor.authorEngin, Aynur
dc.date.accessioned2025-05-04T16:45:56Z
dc.date.available2025-05-04T16:45:56Z
dc.date.issued2025
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjectives: In this study, we aimed to evaluate the change in taurine levels in two diseases [Crimean-Congo hemorrhagic fever (CCHF) and novel coronavirus disease (COVID-19)], which have a significant impact on public health as they frequently cause mortality and morbidity. Methods: This observational, cross-sectional study was conducted between September 15, 2023, and November 30, 2023, at the Emergency Department, Sivas Cumhuriyet University Faculty of Medicine. There were three groups in our study. These groups were 35 COVID-19 patients with confirmed diagnosis, 35 CCHF patients, and a control group consisting of 35 healthy volunteers who were similar to these patient groups in terms of age and gender. Plasma amino acid levels of taurine, beta-alanine, arginine, carnosine, cystine, histidine, lysine, and methionine were measured and compared in these three groups. Results: In the pairwise comparison of the groups, the increase in taurine plasma levels in CCHF (p<0.001) and COVID-19 (p=0.002) patients compared to the control group was statistically significant, whereas the difference between CCHF and COVID-19 patient groups was not significant (p=0.303). Multinomial logistic regression analysis revealed that taurine, beta-alanine, arginine, and lysine levels were significant predictors in differentiating patients with CCHF and COVID-19 from healthy individuals. Conclusions: We concluded that it may be important to determine taurine levels during the treatment and observation processes of these two diseases, which seriously affect public health. This study will contribute to a better understanding of the pathogenesis of the CCHF and COVID-19 diseases.
dc.identifier.doi10.1515/tjb-2024-0092
dc.identifier.endpage115
dc.identifier.issn0250-4685
dc.identifier.issn1303-829X
dc.identifier.issue1
dc.identifier.scopus2-s2.0-105001396777
dc.identifier.scopusqualityQ3
dc.identifier.startpage108
dc.identifier.urihttps://doi.org/10.1515/tjb-2024-0092
dc.identifier.urihttps://hdl.handle.net/20.500.12418/35291
dc.identifier.volume50
dc.identifier.wosWOS:001382662700001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWalter De Gruyter Gmbh
dc.relation.ispartofTurkish Journal of Biochemistry-Turk Biyokimya Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250504
dc.subjectamino acids
dc.subjectCOVID-19
dc.subjectCrimean-Congo hemorrhagic fever
dc.subjectemergency department
dc.subjecttaurine
dc.titleThe significance of taurine for patients with Crimean-Congo hemorrhagic fever and COVID-19 diseases: a cross-sectional study
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu