In-vivo Biocompatibility Evaluation of Different Self-Adhering Composite Resins on Wister Rats

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dc.contributor.authorSaygin, Aysegul
dc.contributor.authorUnal, Murat
dc.contributor.authorKoc, Tulay
dc.contributor.authorIpek, Irem
dc.contributor.authorCandan, Merve
dc.date.accessioned2024-10-26T18:06:01Z
dc.date.available2024-10-26T18:06:01Z
dc.date.issued2021
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractThis study aimed to compare the biocompatibility of two different self-adhering flowable resin composites (SAFCs). 54 polyethylene tubes filled with two different SAFCs [Group V: Vertise Flow (VF), Group F: Fusio Liquid Dentin (FLD), or Group C: empty (Control)] were implanted into the subcutaneous tissue of 18 rats. After 7, 30, and 90 days of implantation, the rats were euthanatized (n=6). The implanted materials were removed with the surrounding tissue for histologic evaluation. The subjects were evaluated in terms of inflammation, fibrous capsule thickness, necrosis, macrophage, and giant cell presence. When the SAFC groups and Group C were compared on days 7, 30, and 90, inflammation, fibrous capsule thickness, and macrophage on the 7th day were statistically significant (p<0.05). Statistically, the giant cell and macrophage criteria were statistically significant on the 7th, 30th, and 90th days in all groups (p<0.05). When the groups were evaluated on different days among themselves, significant differences were observed in terms of local tissue response (p<0.05), while necrosis was found to be statistically insignificant (p>0.05). Biocompatibility was found similar for the SAFCs. These materials used in the study have shown good biocompatibility in rats, and SAFCs can be considered suitable for all restorative treatments.
dc.identifier.doi10.2494/photopolymer.34.579
dc.identifier.endpage585
dc.identifier.issn0914-9244
dc.identifier.issn1349-6336
dc.identifier.issue6
dc.identifier.scopus2-s2.0-85135626556
dc.identifier.scopusqualityQ4
dc.identifier.startpage579
dc.identifier.urihttps://doi.org/10.2494/photopolymer.34.579
dc.identifier.urihttps://hdl.handle.net/20.500.12418/29304
dc.identifier.volume34
dc.identifier.wosWOS:000840560600003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTechnical Assoc Photopolymers,Japan
dc.relation.ispartofJournal of Photopolymer Science and Technology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBiocompatibility
dc.subjectSelf-adhering composite
dc.subjectSubcutaneous tissue
dc.subjectWistar albino rat
dc.titleIn-vivo Biocompatibility Evaluation of Different Self-Adhering Composite Resins on Wister Rats
dc.typeArticle

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