CYTOTOXIC AND ANTIBACTERIAL ACTIVITY OF THE MIXTURE OF OLIVE OIL AND LIME CREAM IN VITRO CONDITIONS

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dc.authoridLin, Kuo-ming -- 0000-0002-2298-0455en_US
dc.contributor.authorSumer, Zeynep
dc.contributor.authorYildirim, Gulay
dc.contributor.authorSumer, Haldun
dc.contributor.authorYildirim, Sahin
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:03:06Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:03:06Z
dc.date.issued2013
dc.department[Sumer, Zeynep] Cumhuriyet Univ, Dept Microbiol, Fac Med, TR-58140 Sivas, Turkey -- [Yildirim, Gulay] Cumhuriyet Univ, Dept Med Eth & Hist Med, TR-58140 Sivas, Turkey -- [Sumer, Haldun] Cumhuriyet Univ, Dept Publ Hlth, Fac Med, TR-58140 Sivas, Turkey -- [Yildirim, Sahin] Cumhuriyet Univ, Dept Pharmacol, Fac Med, TR-58140 Sivas, Turkeyen_US
dc.description.abstractThe mixture of olive oil and lime cream has been traditionally used to treat external burns in the region of Hatay/Antakya and middle Anatolia. Olive oil and lime cream have been employed by many physicians to treat in many ailments in the past. A limited number of studies have shown the antibacterial effect of olive oil and that it does not have any toxic effect on the skin. But we did not find any reported studies on the mixture of olive oil and lime cream. The aim of this paper is to investigate the cytotoxic and antibacterial activity of olive oil and lime cream individually or/and in combination in vitro conditions, by using disk-diffusion method and in cell culture. The main purpose in using this mixture is usually to clear burns without a trace. Agar overlay, MTT (Cytotoxicity assay) and antibacterial susceptibility tests were used to investigate the cytotoxic and antibacterial activity of olive oil and lime cream. We found that lime cream has an antibacterial activity but also cytotoxic on the fibroblasts. On the other hand olive oil has limited or no antibacterial effect and it has little or no cytotoxic on the fibroblasts. When we combined lime cream and olive oil, olive oil reduced its cytotoxic impact. These results suggest that mixture of olive oil and lime cream is not cytotoxic and has antimicrobial activity.en_US
dc.identifier.doi10.4314/ajtcam.v10i4.22en_US
dc.identifier.endpage143en_US
dc.identifier.issn0189-6016
dc.identifier.issue4en_US
dc.identifier.pmid24146514en_US
dc.identifier.scopus2-s2.0-84900732052en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage137en_US
dc.identifier.urihttps://dx.doi.org/10.4314/ajtcam.v10i4.22
dc.identifier.urihttps://hdl.handle.net/20.500.12418/8856
dc.identifier.volume10en_US
dc.identifier.wosWOS:000323318400022en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAFRICAN NETWORKS ETHNOMEDICINESen_US
dc.relation.ispartofAFRICAN JOURNAL OF TRADITIONAL COMPLEMENTARY AND ALTERNATIVE MEDICINESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOlive oilen_US
dc.subjectlime creamen_US
dc.subjectburnen_US
dc.subjectin vitroen_US
dc.subjectcytotoxic activityen_US
dc.subjectantibacterial activityen_US
dc.titleCYTOTOXIC AND ANTIBACTERIAL ACTIVITY OF THE MIXTURE OF OLIVE OIL AND LIME CREAM IN VITRO CONDITIONSen_US
dc.typeArticleen_US

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