Fluoroquinolone Resistance Level in Rectal Swab Taken Before Transrectal Ultrasound Prostate Biopsy

Basit Öğe Kaydı
dc.authoridERGIN, Ismail Emre/0000-0002-3115-0533
dc.authoridOzturk, Abuzer/0000-0002-6090-6133
dc.authoridKorgali, Esat/0000-0003-0318-0353
dc.authoridSaygin, Hasan/0000-0003-2479-7635
dc.authoridBUYUKTUNA, SEYIT ALI/0000-0001-6518-7361
dc.authoridVelibeyoglu, Arslan Fatih/0000-0001-7139-4834
dc.authoridhasbek, mursit/0000-0002-5217-8607
dc.contributor.authorSaygin, Huseyin
dc.contributor.authorOzturk, Abuzer
dc.contributor.authorAsdemir, Aydemir
dc.contributor.authorErgin, Ismail Emre
dc.contributor.authorVelibeyoglu, Arslan Fatih
dc.contributor.authorKirac, Emre
dc.contributor.authorHasbek, Mursit
dc.date.accessioned2024-10-26T18:00:41Z
dc.date.available2024-10-26T18:00:41Z
dc.date.issued2022
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractObjective: It has been shown that antibiotic prophylaxis before transrectal ultrasound prostate biopsy (TRUS-Bx) reduces the incidence of post-biopsy infectious complications. Without the superiority of a particular antibiotic regimen, there are differences in the antibiotic regimens used by clinics. However, recently, there have been serious concerns about TRUS-Bx-related infectious complications due to the increase in fluoroquinolone (FQ)-resistant bacterial strains. To overcome this global problem, alternative antibiotic prophylaxis should be investigated and appropriate antibiotic management should be applied in patients who will undergo TRUS-Bx. This study aimed to determine the antibiotic susceptibility of the rectal flora based on rectal cultures before TRUS-Bx, to systematically determine the basic prevalence of FQ resistance, to investigate the relationship between FQ resistance and the risk of infection after TRUS-Bx, and to determine the susceptibility of Fosfomycin and trimethoprim-sulfamethoxazole (TMP-SMX) as an alternative to the FQ group.Materials and Methods: Rectal swab cultures were taken from each patient to undergo TRUS-Bx two days before the procedure. Two daily doses of 500 mg ciprofloxacin were given orally for one week, starting one hour before the procedure. All patients underwent 12 core biopsies.Results: Antibiograms obtained from rectal swabs showed sensitivity to FQ in 78 patients (89.7%), to Fosfomycin in 85 patients (97.7%), to TMP-SMX in 78 patients (89.7%).Conclusion: Although different antibiotic prophylaxis methods are discussed due to FQ resistance in today's medical practices, FQ sensitivity continues at a high rate of 89.7% in our region and still seems to be a viable prophylaxis method.
dc.identifier.doi10.4274/uob.galenos.2022.2022.1.1
dc.identifier.endpage133
dc.identifier.issn2147-2270
dc.identifier.issue4
dc.identifier.startpage130
dc.identifier.trdizinid1169816
dc.identifier.urihttps://doi.org/10.4274/uob.galenos.2022.2022.1.1
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1169816
dc.identifier.urihttps://hdl.handle.net/20.500.12418/27796
dc.identifier.volume21
dc.identifier.wosWOS:000897687700004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofUroonkoloji Bulteni-Bulletin of Urooncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntibiotic prophylaxis
dc.subjectantibiotic resistance
dc.subjectfluoroquinolones
dc.subjectimage-guided biopsy
dc.subjectprostate
dc.titleFluoroquinolone Resistance Level in Rectal Swab Taken Before Transrectal Ultrasound Prostate Biopsy
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu