MicroRNAs and Cancer; an Overview

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dc.contributor.authorTutar, Lutfi
dc.contributor.authorTutar, Esen
dc.contributor.authorTutar, Yusuf
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:57:49Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:57:49Z
dc.date.issued2014
dc.department[Tutar, Lutfi] Kahramanmaras Sutcu Imam Univ, Fac Sci & Letters, Dept Biol, TR-46050 Kahramanmaras, Turkey -- [Tutar, Esen] Kahramanmaras Sutcu Imam Univ, Grad Sch Nat & Appl Sci, Dept Bioengn & Sci, TR-46050 Kahramanmaras, Turkey -- [Tutar, Yusuf] Cumhuriyet Univ, Fac Pharm, Dept Basic Sci, Div Biochem, TR-58140 Sivas, Turkeyen_US
dc.description.abstractMiRNAs are a family of small, endogenous, and evolutionarily conserved non-coding ribonucleic acids that have been involved in the regulation of several essential, cellular, and functional processes. MicroRNAs are known to play key roles in all types of cancer and function as oncogenes (oncomirs) or tumour-suppressors in up-regulation or down-regulation processes respectively. MiRNAs have potential power to be examined as prognostic and diagnostic biomarkers. Modulating miRNAs, based on two major approaches (miRNA mimics and miRNA antagonists), is used for clinical development of therapeutic miRNAs. This review emphasizes the latest discovery in the field of miRNA research involved in cancer, biomarkers, and therapeutics.en_US
dc.identifier.doi10.2174/1389201015666140519095304en_US
dc.identifier.endpage437en_US
dc.identifier.issn1389-2010
dc.identifier.issn1873-4316
dc.identifier.issue5en_US
dc.identifier.pmid24846068en_US
dc.identifier.scopus2-s2.0-84907161197en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage430en_US
dc.identifier.urihttps://dx.doi.org/10.2174/1389201015666140519095304
dc.identifier.urihttps://hdl.handle.net/20.500.12418/8383
dc.identifier.volume15en_US
dc.identifier.wosWOS:000341916200002en_US
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBENTHAM SCIENCE PUBL LTDen_US
dc.relation.ispartofCURRENT PHARMACEUTICAL BIOTECHNOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiomarkersen_US
dc.subjectcanceren_US
dc.subjectmicroRNAsen_US
dc.subjecttherapeuticsen_US
dc.titleMicroRNAs and Cancer; an Overviewen_US
dc.typeArticleen_US

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