The impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study

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dc.authoridAcer Kasman, Sevtap/0000-0002-4805-0555
dc.authoridAlkan Melikoglu, Meltem/0000-0001-7519-9470
dc.authoridYurdakul, Ozan Volkan/0000-0003-4567-8133
dc.authoridcuzdan balta, nihan/0000-0001-7238-657X
dc.authoridalkan, hakan/0000-0001-8461-9131
dc.authoridcengiz, gizem/0000-0002-0021-7002
dc.authoridTEKEOGLU, IBRAHIM/0000-0003-3395-7178
dc.contributor.authorCengiz, Gizem
dc.contributor.authorNas, Kemal
dc.contributor.authorKeskin, Yasar
dc.contributor.authorKilic, Erkan
dc.contributor.authorSargin, Betul
dc.contributor.authorKasman, Sevtap Acer
dc.contributor.authorAlkan, Hakan
dc.date.accessioned2024-10-26T18:11:47Z
dc.date.available2024-10-26T18:11:47Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractAim Nail involvement is common in psoriatic arthritis. This study assesses clinical characteristics, nail psoriasis prevalence, and impact of nail psoriasis on disease activity in patients with psoriatic arthritis (PsA). Method This cross-sectional multicenter study was conducted by the Turkish League Against Rheumatism using PsA patients recruited from 25 centers. Demographic and clinical characteristics of PsA patients, such as disease activity measures, quality of life, and nail involvement findings were assessed during routine follow-up examinations. Patients were divided into two groups according to the presence or absence of nail psoriasis and compared using the chi(2) test or Fisher exact test for categorical variables and the t-test or Mann-Whitney U test for continuous variables. Results In 1122 individuals with PsA, 645 (57.5%) displayed nail psoriasis. The most frequent features of fingernails were ridges (38%), followed by pitting (21%) and onycholysis (19%). More females were present in both groups (with and without nail psoriasis; 64% vs 67%, P < 0.282). Patients with nail psoriasis were older, indicated more pain and fatigue, experienced greater swelling, tender joint counts, and skin disease severity, and had a higher disease activity score compared with those without nail psoriasis (all P < 0.05). Conclusion We demonstrate an increased prevalence of nail psoriasis observed in patients with psoriatic arthritis. Patients with nail involvement experience increased disease activity, lower quality of life, and diminished mental and physical status compared with those without nail involvement.
dc.identifier.doi10.1111/1756-185X.14442
dc.identifier.endpage50
dc.identifier.issn1756-1841
dc.identifier.issn1756-185X
dc.identifier.issue1
dc.identifier.pmid36165674
dc.identifier.scopus2-s2.0-85138726192
dc.identifier.scopusqualityQ3
dc.identifier.startpage43
dc.identifier.urihttps://doi.org/10.1111/1756-185X.14442
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30829
dc.identifier.volume26
dc.identifier.wosWOS:000859954300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofInternational Journal of Rheumatic Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectclinical characteristics
dc.subjectdisease activity
dc.subjectnail involvement
dc.subjectnail psoriasis
dc.subjectpsoriatic arthritis
dc.subjectquality of life
dc.titleThe impact of nail psoriasis on disease activity, quality of life, and clinical variables in patients with psoriatic arthritis: A cross-sectional multicenter study
dc.typeArticle

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