Exploring the therapeutic and anti-tumor properties of morusin: a review of recent advances

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dc.authoridKhan, Khushbukhat/0000-0002-9946-9057
dc.authoridAlmarhoon, Zainab M./0000-0001-8196-2612
dc.authoridSharifi-Rad, Javad/0000-0002-7301-8151
dc.authoridKhan, Zeeshan/0000-0002-4461-9863
dc.contributor.authorHafeez, Amna
dc.contributor.authorKhan, Zeeshan
dc.contributor.authorArmaghan, Muhammad
dc.contributor.authorKhan, Khushbukhat
dc.contributor.authorGurer, Eda Sonmez
dc.contributor.authorRazis, Ahmad Faizal Abdull
dc.contributor.authorModu, Babagana
dc.date.accessioned2024-10-26T18:11:34Z
dc.date.available2024-10-26T18:11:34Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractMorusin is a natural product that has been isolated from the bark of Morus alba, a species of mulberry tree. It belongs to the flavonoid family of chemicals, which is abundantly present in the plant world and is recognized for its wide range of biological activities. Morusin has a number of biological characteristics, including anti-inflammatory, anti-microbial, neuro-protective, and antioxidant capabilities. Morusin has exhibited anti-tumor properties in many different forms of cancer, including breast, prostate, gastric, hepatocarcinoma, glioblastoma, and pancreatic cancer. Potential of morusin as an alternative treatment method for resistant malignancies needs to be explored in animal models in order to move toward clinical trials. In the recent years several novel findings regarding the therapeutic potential of morusin have been made. This aim of this review is to provide an overview of the present understanding of morusin's beneficial effects on human health as well as provide a comprehensive and up-to-date discussion of morusin's anti-cancer properties with a special focus on in vitro and in vivo studies. This review will aid future research on the creation of polyphenolic medicines in the prenylflavone family, for the management and treatment of cancers.
dc.identifier.doi10.3389/fmolb.2023.1168298
dc.identifier.issn2296-889X
dc.identifier.pmid37228582
dc.identifier.scopus2-s2.0-85159926321
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3389/fmolb.2023.1168298
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30735
dc.identifier.volume10
dc.identifier.wosWOS:000993733200001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherFrontiers Media Sa
dc.relation.ispartofFrontiers in Molecular Biosciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectmorusin
dc.subjectnatural compound
dc.subjectanti-cancer activity
dc.subjectpolyphenol
dc.subjectresistant malignancies
dc.titleExploring the therapeutic and anti-tumor properties of morusin: a review of recent advances
dc.typeReview Article

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