Antibacterial efficacy and remineralization capacity of glycyrrhizic acid added casein phosphopeptide-amorphous calcium phosphate

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dc.authoridOZNURHAN, Fatih/0000-0002-7797-0932
dc.contributor.authorSahin, Feride
dc.contributor.authorOznurhan, Fatih
dc.date.accessioned2024-10-26T18:04:00Z
dc.date.available2024-10-26T18:04:00Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractThe aim was to evaluate remineralization capacity and antibacterial efficiency of Tooth Mousse and various amounts of glycyrrhizic acid added Tooth Mousse on primary tooth enamel. Three groups were formed; Group 1 (CPP-ACP), Group 2 (CPP-ACP + 5% glycyrrhizic acid), and Group 3 (CPP-ACP + 10% glycyrrhizic acid) in order to evaluate remineralization capacity. Enamel samples were immersed in demineralization solution and then remineralization agents were applied. Surface microhardness and SEM analyses were performed at the beginning, after demineralization and remineralization. For antibacterial tests, four groups were formed; Group 1, Group 2 and Group 3 and Group 4 (control). Biofilms were then exposed to 10% sucrose eight times per day for 7 days. After biofilm growth period, samples were treated with materials to evaluate antibacterial efficiency except control group. After application of materials, samples were incubated 2 more days at 37 degrees C and at the end of this period, absorbance values of biofilms were determined and data were analyzed. An increase in microhardness values was Group 2 > Group 3 > Group 1, respectively, but there were no significant differences. After remineralization, microhardness values showed significant increases when compared to demineralized groups, but there was no significant difference. All groups showed decreased absorbance value of biofilm when compared with control group but they were insignificant. It was observed that both in Group 2 and Group 3, glycyrrhizic acid did not have a negative effect on remineralization and although they have an increase, it was insignificant. Although glycyrrhizic acid added CPP-ACP groups showed increased antibacterial activity, they were not statistically significant.
dc.description.sponsorshipScientific Research Project Fund Cumhuriyet University [DIS-209]
dc.description.sponsorshipThis work was supported by the Scientific Research Project Fund Cumhuriyet University (Grant No. DIS-209).
dc.identifier.doi10.1002/jemt.23465
dc.identifier.endpage754
dc.identifier.issn1059-910X
dc.identifier.issn1097-0029
dc.identifier.issue7
dc.identifier.pmid32191375
dc.identifier.scopus2-s2.0-85082055358
dc.identifier.scopusqualityQ1
dc.identifier.startpage744
dc.identifier.urihttps://doi.org/10.1002/jemt.23465
dc.identifier.urihttps://hdl.handle.net/20.500.12418/28676
dc.identifier.volume83
dc.identifier.wosWOS:000520526700001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofMicroscopy Research and Technique
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectabsorbance value
dc.subjectantibacterial effect
dc.subjectbiofilm
dc.subjectCPP-ACP
dc.subjectdemineralization
dc.subjectglycyrrhizic acid
dc.subjectmicrohardness
dc.subjectremineralization
dc.subjectVickers
dc.titleAntibacterial efficacy and remineralization capacity of glycyrrhizic acid added casein phosphopeptide-amorphous calcium phosphate
dc.typeArticle

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