Optimization of Paracetamol and Chloramphenicol Removal by Novel Activated Carbon Derived from Sawdust Using Response Surface Methodology

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dc.authoridATES, AYTEN/0000-0002-0806-4549
dc.authoridATTIA, Afef/0000-0003-2441-8375
dc.contributor.authorRomdhani, Mohamed
dc.contributor.authorAttia, Afef
dc.contributor.authorCharcosset, Catherine
dc.contributor.authorMahouche-Chergui, Samia
dc.contributor.authorAtes, Ayten
dc.contributor.authorDuplay, Joelle
dc.contributor.authorAmar, Raja Ben
dc.date.accessioned2025-05-04T16:45:40Z
dc.date.available2025-05-04T16:45:40Z
dc.date.issued2023
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractParacetamol (PCT) and chloramphenicol (CPL) can have unfavorable impacts on human health, as well as on natural ecosystems. These substances contribute to the aquatic environment's contamination and disturb the performance of municipal wastewater treatment systems, causing ecosystem disruption and microbial resistance. In this study, activated carbon produced from sawdust (ACs) was synthesized utilizing the chemical activation process for the removal of both PCT and CPL compounds from an aqueous solution. ACs has a primarily microporous structure with a significant specific surface area of 303-1298 m(2)/g, total pore volume of 0.462 cm(3)/g and bimodal distribution of pores of 0.73-1.7 nm. The removal efficiencies for PCT and CPL with the low-cost activated carbon, determined at the optimum dose (750 mg/L for PCT and 450 mg/L for CPL), were significantly high at 85% and 98%, respectively. The adsorption kinetics for both pharmaceuticals exhibited a quick initial decline. For PCT and CPL adsorption, the equilibrium was attained after just 20 and 90 min, respectively. The Langmuir isotherm model and the pseudo-second-order kinetics model offered the best fits for the adsorption of both compounds. Additionally, the central composite design (CCD) and Box-Behnken design (BBD) were used to optimize the experimental adsorption conditions using a response surface methodology (RSM). On the basis of the findings, it is evident that activated carbon made from sawdust may be used as a new, effective alternative adsorbent for removing PCT and CPL in aqueous environments.
dc.identifier.doi10.3390/su15032516
dc.identifier.issn2071-1050
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85147962572
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/su15032516
dc.identifier.urihttps://hdl.handle.net/20.500.12418/35179
dc.identifier.volume15
dc.identifier.wosWOS:000930446900001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherMDPI
dc.relation.ispartofSustainability
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250504
dc.subjectparacetamol
dc.subjectchloramphenicol
dc.subjectactivated carbon
dc.subjectadsorption
dc.subjectresponse surface
dc.subjectmethodology
dc.subjectexperimental design
dc.titleOptimization of Paracetamol and Chloramphenicol Removal by Novel Activated Carbon Derived from Sawdust Using Response Surface Methodology
dc.typeArticle

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