Hypertensive response to exercise in dipper and non-dipper normotensive diabetics

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dc.contributor.authorKucukdurmaz, Zekeriya
dc.contributor.authorKaravelioglu, Yusuf
dc.contributor.authorKarapinar, Hekim
dc.contributor.authorGul, Ibrahim
dc.contributor.authorYilmaz, Ahmet
dc.contributor.authorYarlioglues, Mikail
dc.contributor.authorAkpek, Mahmut
dc.contributor.authorKaya, Mehmet Gungor
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T09:57:53Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T09:57:53Z
dc.date.issued2014
dc.department[Kucukdurmaz, Zekeriya -- Karapinar, Hekim -- Gul, Ibrahim -- Yilmaz, Ahmet] Cumhuriyet Univ, Sch Med, Dept Cardiol, Sivas, Turkey -- [Karavelioglu, Yusuf] Corum State Hosp, Dept Cardiol, Corum, Turkey -- [Yarlioglues, Mikail -- Akpek, Mahmut -- Kaya, Mehmet Gungor] Erciyes Univ, Sch Med, Dept Cardiol, TR-38039 Kayseri, Turkeyen_US
dc.description.abstractNon-dipper blood pressure (NDP) as an indicator of autonomic dysfunction could be associated with hypertensive response to exercise (HRE) in diabetic patients. HRE was determined as a predictor of development of unborn hypertension. We aimed to investigate if any correlation among NDP and HRE in normotensive type 2 diabetic patients. A total of 59 consecutive type 2 diabetic patients without history of hypertension and with normal blood pressure (BP) on ambulatory blood pressure monitoring (ABPM) were enrolled to the study. We divided the study population in to two groups depending on their BP on ABPM as dipper (group 1) or non-dipper (group 2). There were 22 patients (mean age 49.5 +/- 7 and 10 male) in group 1 and 37 patients (mean age 53.1 +/- 10 and 14 male) in group 2. Daytime diastolic and mean BP of dippers and night time systolic and mean BP of non-dippers were significantly higher. HRE was not significantly different between groups (59% vs. 62%, p = 0.820). Hemodynamic parameters during the exercise test were similar. At multivariate linear regression analysis, resting office systolic blood pressure (SBP) (r = 0.611, p < 0.001), male sex (r = 0.266, p = 0.002) and age (r = 0.321, p = 0.010) were independently correlated with peak exercises SBP. Logistic regression analyses identified the resting office SBP (OR 1.191, 95% CI 1.080-1.313; p<0.001) and age (OR 1.161, 95% CI 1.038-1.298; p = 0.012) were independent predictors of HRE. This study revealed that HRE is not related with non-dipper BP in diabetic patients. This study could inspire to further studies to explore the main reasons of HRE in diabetes mellitus.en_US
dc.identifier.doi10.3109/10641963.2013.789050en_US
dc.identifier.endpage279en_US
dc.identifier.issn1064-1963
dc.identifier.issn1525-6006
dc.identifier.issue5en_US
dc.identifier.pmid24878253en_US
dc.identifier.scopus2-s2.0-84903792122en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage275en_US
dc.identifier.urihttps://dx.doi.org/10.3109/10641963.2013.789050
dc.identifier.urihttps://hdl.handle.net/20.500.12418/8394
dc.identifier.volume36en_US
dc.identifier.wosWOS:000338997700001en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS INCen_US
dc.relation.ispartofCLINICAL AND EXPERIMENTAL HYPERTENSIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiabetes mellitusen_US
dc.subjectdipperen_US
dc.subjecthypertensionen_US
dc.subjecthypertensive response to exerciseen_US
dc.subjectnon-dipperen_US
dc.titleHypertensive response to exercise in dipper and non-dipper normotensive diabeticsen_US
dc.typeArticleen_US

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