Does Polyp-Originated Growing have Prognostic Significance for Stage 1 Endometrioid-Type Endometrial Cancer?

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dc.authoridGunakan, Emre/0000-0001-8854-8190
dc.authoridHABERAL REYHAN, ASUMAN NIHAN/0000-0001-9852-9911
dc.authoridHaberal, Ali/0000-0002-1486-7209
dc.authoridKucukyildiz, Irem/0000-0002-6604-0713
dc.contributor.authorKucukyildiz, Irem Alyazici
dc.contributor.authorGunakan, Emre
dc.contributor.authorAkilli, Huseyin
dc.contributor.authorHaberal, Asuman Nihan
dc.contributor.authorKuscu, Esra
dc.contributor.authorHaberal, Ali
dc.contributor.authorAyhan, Ali
dc.date.accessioned2024-10-26T18:09:26Z
dc.date.available2024-10-26T18:09:26Z
dc.date.issued2020
dc.departmentSivas Cumhuriyet Üniversitesi
dc.description.abstractPurpose Endometrioid-type endometrial cancer is usually diagnosed in the early stages and has a good prognosis. Patients with stage 1 disease have survival rates over 95%. Tumor factors affect survival in these patients, but polyp-originated growing has not been sufficiently discussed in the literature. This study aimed to determine the effect of polyp-originated growing in stage 1 endometrioid-type endometrial cancer and to provide a review of the literature. Methods This study includes 318 stage 1 endometrioid-type endometrial cancer patients. The patients were divided into two groups based on the tumor origin. Group I included patients with polyp-originated growing tumors, and Group II included patients with endometrial surface-originated growing tumors. Results Groups I and II included 39 and 279 patients, respectively. The general properties of the patients were similar; there were no significant differences. The univariate survival analyses showed that overall survival for Groups I and II was 65.5 and 83.6 months, respectively; this difference was statistically significant (p = 0.002). The multivariate analysis of age, maximum tumor diameter, tumor origin, lymphovascular space involvement, myometrial invasion depth and tumor grade showed that polyp-originated growing was independently and significantly associated with overall survival (HR 4.05; 95% CI 1.2-13.5; p = 0.023). Conclusion Polyp-originated growing may be a prognostic factor for early stage endometrioid-type endometrial cancer. The prognostic effect of polyp-originated growing is not well known, and further investigation is necessary.
dc.identifier.doi10.1007/s40944-019-0351-9
dc.identifier.issn2363-8397
dc.identifier.issn2363-8400
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85075754591
dc.identifier.scopusqualityQ4
dc.identifier.urihttps://doi.org/10.1007/s40944-019-0351-9
dc.identifier.urihttps://hdl.handle.net/20.500.12418/30101
dc.identifier.volume18
dc.identifier.wosWOS:000501019100001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer India
dc.relation.ispartofIndian Journal of Gynecologic Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEndometrial polyp
dc.subjectEndometrioid-type endometrial cancer
dc.subjectEndometrial cancer
dc.subjectOverall survival
dc.titleDoes Polyp-Originated Growing have Prognostic Significance for Stage 1 Endometrioid-Type Endometrial Cancer?
dc.typeArticle

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