Biomechanical properties of ciprofloxacin loaded bone cement

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dc.authoridOztemur, Zekeriya -- 0000-0003-2134-8797en_US
dc.contributor.authorAslan, Talip Teoman
dc.contributor.authorOztemur, Zekeriya
dc.contributor.authorCifci, Mahmut
dc.contributor.authorTezeren, Gunduz
dc.contributor.authorOzturk, Hayati
dc.contributor.authorBulut, Okay
dc.date.accessioned2019-07-27T12:10:23Z
dc.date.accessioned2019-07-28T10:03:09Z
dc.date.available2019-07-27T12:10:23Z
dc.date.available2019-07-28T10:03:09Z
dc.date.issued2013
dc.department[Aslan, Talip Teoman -- Oztemur, Zekeriya -- Cifci, Mahmut -- Tezeren, Gunduz -- Ozturk, Hayati -- Bulut, Okay] Cumhuriyet Univ, Tip Fak, Ortopedi & Travmatol Anabilim Dali, Sivas, Turkeyen_US
dc.description.abstractObjective: The purpose of this study was to investigate the biomechanical properties of bone cement used in joint replacement surgery after the addition of ciprofloxacin. Methods: The first group received bone cement only and served as a control for the 4 groups where 500 mg, 1000 mg, 1500 mg and 2000 mg of ciprofloxacin were added to yield 40 g of bone cement. Axial compression tests were conducted using a 50,000 Newton capacity tension-compression testing device. Results: While axial compression strength at failure was 80.2 +/- 4.3 MPa in the control group, values in the ciprofloxacin-treated groups decreased with rising concentration of ciprofloxacin to 74.5 +/- 5.4 MPa, 70.6 +/- 4.8 MPa, 70.5 +/- 4.7 MPa, and 69.3 +/- 3.4 MPa. Conclusion: Bone cement with addition of 500 to 1500 mg ciprofloxacin maintained mechanical axial strength values above 70.0 MPa recommended by American Society for Testing and Materials and can be safely used in joint replacement surgery.en_US
dc.identifier.doi10.3944/AOTT.2013.2806en_US
dc.identifier.endpage59en_US
dc.identifier.issn1017-995X
dc.identifier.issue1en_US
dc.identifier.pmid23549318en_US
dc.identifier.scopus2-s2.0-84880409759en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage55en_US
dc.identifier.urihttps://dx.doi.org/10.3944/AOTT.2013.2806
dc.identifier.urihttps://hdl.handle.net/20.500.12418/8888
dc.identifier.volume47en_US
dc.identifier.wosWOS:000319232000011en_US
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTURKISH ASSOC ORTHOPAEDICS TRAUMATOLOGYen_US
dc.relation.ispartofACTA ORTHOPAEDICA ET TRAUMATOLOGICA TURCICAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAxial compressionen_US
dc.subjectbone cementen_US
dc.subjectciprofloxacinen_US
dc.subjectPMMAen_US
dc.titleBiomechanical properties of ciprofloxacin loaded bone cementen_US
dc.typeArticleen_US

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