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Epigenetics and Autoimmunity
(Cambridge Scholar publication, 2021)
The immune system is a complex system that forms the defense mechanism
against diseases in a living thing, recognizes and destroys pathogens and
tumor cells, and protects the body from foreign and harmful substances.
...
Autoimmunity and genetics
(Cambridge Scholar publication, 2021)
Unlike 50 years ago, autoimmunity is today a widely recognized
phenomenon with registered cases encompassing more than 5% of the world
populace with at least 40 different autoimmune disorders (Mori et al. 2005).
Notwithstanding ...
Melatonin levels and microRNA (miRNA) relative expression profile in the follicular ambient microenvironment in patients undergoing in vitro fertilization process
(2021)
Abstract
Purpose
Intrafollicular fluid (IFF) melatonin plays a decisive role in maintaining granulosa cells’ DNA integrity and protects them against apoptosis. It reduces oxidative stress and improves the oocyte quality ...
Synthesis of PEGylated nanographene oxide as a nanocarrier for docetaxel drugs and anticancer activity on prostate cancer cell lines
(SAGE Publishing, 2021)
Graphene oxide (GO) has recently been considered one of the most promising carbon derivatives in nanotechnology.
It has many excellent features such as tumor targeting ability, biocompatibility and low toxicity.
Therefore, ...
Investigation of Binding behaviour of a water-soluble gallium (III) phthalocyanine with double-stranded and G-quadruplex DNA via experimental and computational methods
(2021/9/15)
DNA is an important target for the development of chemotherapeutic drug design due to increased and uncontrolled cell proliferation of cancer cells. In the present study, the affinity of water-soluble gallium(III) ...
The evaluation of intracellular energy metabolism in prediabetic patients and patients newly diagnosed with type 2 diabetes mellitus
(2021)
Background/aim: Increased susceptibility to infections is a serious problem in diabetics. Impairment in the energy metabolism of the
immune system is the main source of the problem. Early diagnosis of the impairment in ...
BSA/DNA binding behavior and the photophysicochemical properties of novel water soluble zinc (II) phthalocyanines directly substituted with piperazine groups
(Springer, 2021/05/04)
In the current research, two novel zinc(II) phthalocyanines (ZnPcs) (1 and 2) directly connecting with 4-(4-methylpiperazin-1-yl)phenyl groups have been synthesized through the Suzuki–Miyaura coupling reaction. These ZnPcs ...
Interaction of water soluble cationic gallium (III) phthalocyanines with different G-quadruplex DNAs
(Elsevier, 2021/11/1)
Small molecule-G-quadruplex DNA interaction has been gained considerable interest due to existence of G-quadruplex structures in telomeres and promotor regions of proto-oncogenes. In the present study, the interaction of ...
IL‑13 Gene Polymorphisms (‑1112 C/T and ‑1512 A/C) in Patients with Chronic and Aggressive Periodontitis: Effects on GCF and Outcome of Periodontal Therapy
(Medical and Dental Consultants’ Association of Nigeria, 2021)
Background: IL‑13 is the key cytokine in the regulation of inflammatory with
an autoimmune disease and has an anti‑inflammatory effect. Aims: This study
aimed to compare IL‑13 (‑1112 C/T and ‑1512 A/C) gene polymorphisms
in ...
Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome
(CMB Association Publiher, 2021)
Although there is not yet full clarity of the pathogenesis of fibromyalgia syndrome (FM), central sensitization is considered to be responsible. The purpose of this study was to measure the plasma levels of potassium ion ...