Browsing Fakülteler by Title
Now showing items 1834-1853 of 2184
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Synthesis, and docking studies of novel tetrazole S-alkyl derivatives as antimicrobial agents
(Taylor & Francis, 01.09.2022)A series of novel tetrazole-S-alkyl-piperazine derivatives were synthesized and evaluated for their antifungal activity against C. albicans (ATCC 24433), C. krusei (ATCC 6258) and C. parapsilosis (ATCC 22019) and ... -
Synthesis, and docking studies of novel tetrazole-S-alkyl derivatives as antimicrobial agents
(07.01.2023)A series of novel tetrazole-S-alkyl-piperazine derivatives were synthesized and evaluated for their antifungal activity against C. albicans (ATCC 24433), C. krusei (ATCC 6258) and C. parapsilosis (ATCC 22019) and ... -
Synthesis, antimicrobial activity and molecular docking study of benzyl functionalized benzimidazole silver(I) complexes
(2023)In this study, a series of N-functionalized benzimidazole silver(I) complexes were prepared and characterized by FT-IR, 1H, 13C{1H} NMR spectroscopy, and elemental analysis. Synthesized N-benzylbenzimidazole silver(I) ... -
Synthesis, biological evaluation and in silico studies of novel thiadiazole-hydrazone derivatives for carbonic anhydrase inhibitory and anticancer activities
(04.08.2023)ABSTRACT Thiadiazole and hydrazone derivatives (5a–5i) were synthesized and their chemical structures were verified and described by 1 H NMR, 13 C NMR, and HRMS spectra. Three cancer cell lines (MCF-7, MDA, and ... -
Synthesis, Biological Evaluation and In Silico Studies of Some 2‐Substituted Benzoxazole Derivatives as Potential Anticancer Agents to Breast Cancer
(2022)In an attempt to develop potent and selective anticancer agents, some 5- or 6- and N-substituted benzoxazol-2-carbox amide derivatives were designed, synthesized, and evaluated for their cyclooxygenase inhibitory, antioxidant, ... -
Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives
(Elsevier, 2022/12/05)A new series of imidazolyl hydrazone derivatives IA (1-12) were prepared from a condensation reaction between indoline-2,3-dione (isatin) and 2-benzylidenehydrazinecarboximidamide derivatives. The structure of compounds ... -
Synthesis, characterization, and application of polyacrylamide/carmine polymer nanomaterial as an effective solid-phase material for ultrasonic-assisted solid-phase microextraction of aluminum and chromium in vegetable samples
(2022)Here, a new and inexpensive polymer nanomaterial consisting of polyacrylamide and carmine (PAM-CR) was synthesized to provide selective extraction of aluminum and chromium from vegetable samples prior to their determination ... -
Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes
(2021)Microorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals. Inhibition ... -
Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes†
(The Royal Society of Chemistry, 2 November)Microorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals. Inhibition ... -
Synthesis, characterization, antimicrobial and antibiofilm activity, and molecular docking analysis of NHC precursors and their Ag-NHC complexes†
(The Royal Society, 2021)Microorganisms attach to surfaces and interfaces and form biofilms which create a sheltered area for host cell response. Therefore, biofilms provide troubles in fields such as medicine, food, and pharmaceuticals. Inhibition ... -
Synthesis, characterization, biological and DFT studies of chargetransfer complexes of antihyperlipidemic drug atorvastatin calcium with Iodine, Chloranil, and DDQ
(Elsevier, 2022)Extremely coloured charge-transfer complexes (CTCs) of antihyperlipidemic drug, atorvastatin calcium (ATC) acting as n-electron donor with the electron acceptors, namely, iodine as r-acceptor, 2,3,4,6-tetra chloro-1,4- ... -
Synthesis, computational analyses, antibacterial and antibiofilm properties of nicotinamide derivatives
(Ağustos 20)Newly designed nicotinamide derivatives were synthesized and characterized using spectral techniques (IR, 1H-NMR, 13C-NMR, and MS). Moreover, these compounds are investigated computationally. B3LYP/6–31 + G(d,p) level is ... -
Synthesis, docking studies, in vitro cytotoxicity evaluation and DNA damage mechanism of new tyrosine-based tripeptides
(Wiley, 2023)Peptides are one of the leading groups of compounds that have been the subject of a great deal of biological research and still continue to attract researchers' attention. In this study, a series of tripeptides based on ... -
Synthesis, identification, density functional and Hirshfeld surface studies of 2,20-disulfanediylbis(tetrahydro-4Hcyclopenta[ d][1,3,2]dioxaphosphole-2-sulfide)
(Wiley, 2021)The new compound 2,20-disulfanediylbis (tetrahydro-4H-cyclo penta[d][1,3,2] dioxaphosphole 2-sulfide), the dimeric form of 2-mercaptotetrahydro-4H-cyclopenta [d] [1,3,2] dioxaphosphole 2-sulfide, has been synthesized and ... -
Synthesis, in silico and investigation of anti-breast cancer activity of new diphenyl urea derivatives: Experimental and computational study
(Ekim 2022)Cancer is a complex disease that requires multidisciplinary treatment. One of the most common cancers is breast cancer, and these cancers are usually estrogen receptor-positive. Today, chemotherapy, as well as surgery, ... -
Synthesis, in silico and investigation of anti-breast cancer activity of new diphenyl urea derivatives: Experimental and computational study
(2022)Cancer is a complex disease that requires multidisciplinary treatment. One of the most common cancers is breast cancer, and these cancers are usually estrogen receptor-positive. Today, chemotherapy, as well as surgery, has ... -
Synthesis, in vitro anticancer activities, and quantum chemical investigations on 1,3-bis-(2-methyl-2-propenyl)benzimidazolium chloride and its Ag(I) complex
(2021)1,3-Bis-(2-methyl-2-propenyl)benzimidazolium chloride and its Ag(I) complex are synthesized and the structures are elucidated using spectroscopies techniques. The molecular and crystal structures of the benzimidazolium ... -
Synthesis, In Vitro Cytotoxicity, and DFT Studies of Novel 2- Amino Substituted Benzonaphthyridines as PDK1 Inhibitors
(2022)The present work emphasizes the utility of 2,4-dichloro-5- methylbenzo[h][1,6]naphthyridine as starting precursors. The reaction of 2,4-dichloro-5-methylbenzo[h][1,6]naphthyridine with a variety of aliphatic and aromatic ... -
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
(2021)A new class of cyanopyridine derivatives (10a-e and 11a-e) containing the phenylurea unit was synthesized and tested against some metabolic enzymes including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and ... -
Synthesis, molecular docking, and biological activities of new cyanopyridine derivatives containing phenylurea
(Wiley-VCH GmbH, Weinheim, 2021/4)A new class of cyanopyridine derivatives (10a–e and 11a–e) containing the phenylurea unit was synthesized and tested against some metabolic enzymes including acetylcholinesterase (AChE), butyrylcholinesterase (BChE), ...